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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KRNY icon
626
Kearny Financial
KRNY
$604M
$12M 0.02%
1,612,987
+1,339,062
+489% +$9.24M
TROW icon
627
T. Rowe Price
TROW
$24.2B
$11.9M 0.02%
116,030
-83,000
-42% -$8.57M
NTST
628
NETSTREIT Corp
NTST
$2.14B
$11.8M 0.02%
670,000
-330,000
-33% -$6.01M
SMCI icon
629
Super Micro Computer
SMCI
$19B
$11.8M 0.02%
402,700
-3,700
-0.9% -$152K
WSM icon
630
Williams-Sonoma
WSM
$29.1B
$11.8M 0.02%
66,000
+14,000
+27% +$2.62M
ATXS
631
DELISTED
Astria Therapeutics
ATXS
$11.8M 0.02%
900,000
+66,000
+8% +$788K
DPZ icon
632
Domino's
DPZ
$11.9B
$11.7M 0.02%
28,039
+18,600
+197% +$7.75M
FE icon
633
FirstEnergy
FE
$27.4B
$11.7M 0.02%
+260,400
New +$12M
ON icon
634
ON Semiconductor
ON
$18.6B
$11.6M 0.02%
213,300
-59,000
-22% -$3.03M
TEX icon
635
Terex
TEX
$7.47B
$11.5M 0.02%
+215,000
New +$10.9M
LADR
636
Ladder Capital
LADR
$1.21B
$11.4M 0.02%
1,040,832
+544,830
+110% +$5.92M
NERV icon
637
Minerva Neurosciences
NERV
$207M
$11.4M 0.02%
+2,838,000
New +$10.5M
LFACU
638
Leapfrog Acquisition Corp Units
LFACU
$11.3M 0.02%
+1,125,000
New +$11.3M
WCC
639
WESCO International
WCC
$18.1B
$11.3M 0.02%
46,000
-227,265
-83% -$55.7M
CLX icon
640
Clorox
CLX
$12.8B
$11.1M 0.02%
+110,153
New +$12M
IONS icon
641
Ionis Pharmaceuticals
IONS
$9.06B
$11.1M 0.02%
140,000
-1,175,000
-89% -$88.5M
HPQ icon
642
HP
HPQ
$25.8B
$11M 0.02%
493,836
-111,200
-18% -$2.83M
CBLL
643
CeriBell Inc
CBLL
$692M
$11M 0.02%
+500,000
New +$7.76M
BG icon
644
Bunge Global
BG
$20.9B
$10.9M 0.02%
122,200
-5,300
-4% -$489K
CBC
645
Central Bancompany Inc
CBC
$7.99B
$10.8M 0.02%
+447,199
New +$10.5M
FHN icon
646
First Horizon
FHN
$12.1B
$10.8M 0.02%
449,893
+235,000
+109% +$5.24M
MNKD icon
647
MannKind Corp
MNKD
$1.24B
$10.7M 0.02%
1,894,000
+200,000
+12% +$1.1M
PTCT icon
648
PTC Therapeutics
PTCT
$5.91B
$10.7M 0.02%
141,000
-150,000
-52% -$10.9M
A icon
649
Agilent Technologies
A
$39.9B
$10.7M 0.02%
78,520
-55,074
-41% -$7.92M
WY icon
650
Weyerhaeuser
WY
$18.3B
$10.7M 0.02%
450,800
-413,248
-48% -$9.56M
24 25
26
27 28

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.