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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DCOM icon
601
Dime Commercial Bancshares
DCOM
$1.81B
$13.3M 0.02%
+442,719
New +$12.8M
FFIV icon
602
F5
FFIV
$23.5B
$13.3M 0.02%
52,100
-200
-0.4% -$53.8K
TDWD
603
Tailwind 2.0 Acquisition Corp
TDWD
$237M
$13.3M 0.02%
+1,350,000
New +$13.3M
IGAC
604
Invest Green Acquisition Corp
IGAC
$13.3M 0.02%
+1,350,000
New +$13.3M
STEP icon
605
StepStone Group
STEP
$4.14B
$13.1M 0.02%
+203,695
New +$12.9M
FYBR
606
DELISTED
Frontier Communications
FYBR
$13.1M 0.02%
342,886
-100,521
-23% -$3.8M
ADUS icon
607
Addus HomeCare
ADUS
$2.22B
$13M 0.02%
120,778
+14,314
+13% +$1.64M
TGNA
608
DELISTED
TEGNA Inc
TGNA
$12.9M 0.02%
667,172
+42,172
+7% +$833K
EG icon
609
Everest Group
EG
$14.2B
$12.9M 0.02%
37,881
+12,200
+48% +$4.03M
CEPF
610
Cantor Equity Partners IV
CEPF
$594M
$12.8M 0.02%
1,250,000
– –
SLG icon
611
SL Green Realty
SLG
$3.86B
$12.8M 0.02%
280,000
-125,000
-31% -$6.17M
FR icon
612
First Industrial Realty Trust
FR
$8.4B
$12.8M 0.02%
223,703
-51,053
-19% -$2.85M
PTC icon
613
PTC
PTC
$16B
$12.7M 0.02%
73,100
-11,000
-13% -$2.04M
SKWD icon
614
Skyward Specialty Insurance
SKWD
$2.66B
$12.7M 0.02%
+248,708
New +$12M
PRQR icon
615
ProQR Therapeutics
PRQR
$268M
$12.6M 0.02%
6,253,467
– –
HIG icon
616
Hartford Financial Services
HIG
$39.6B
$12.6M 0.02%
91,532
+25,600
+39% +$3.38M
TKO icon
617
TKO Group
TKO
$13.7B
$12.5M 0.02%
59,900
-2,900
-5% -$564K
LPCVU
618
Launchpad Cadenza Acquisition Corp I Unit
LPCVU
$201M
$12.5M 0.02%
+1,250,000
New +$12.5M
ADACU
619
American Drive Acquisition Co Units
ADACU
$12.5M 0.02%
+1,250,000
New +$12.5M
THG icon
620
Hanover Insurance
THG
$8.06B
$12.4M 0.02%
68,000
-130,000
-66% -$23.4M
REG icon
621
Regency Centers
REG
$14.1B
$12.3M 0.02%
178,600
+29,800
+20% +$2.09M
PRCT icon
622
Procept Biorobotics
PRCT
$1.14B
$12.2M 0.02%
+389,278
New +$12.9M
WLTH
623
Wealthfront Corp
WLTH
$1.44B
$12.1M 0.02%
+891,600
New +$11.8M
TPR icon
624
Tapestry
TPR
$32.7B
$12.1M 0.02%
94,800
-7,523
-7% -$860K
BLZR
625
Trailblazer Acquisition Corp
BLZR
$349M
$12M 0.02%
+1,200,000
New +$12.1M
23 24
25
26 27

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.