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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HBNC icon
551
Horizon Bancorp
HBNC
$1.05B
$16.3M 0.02%
963,397
+424,896
+79% +$7.04M
HCACU
552
Hall Chadwick Acquisition Corp Unit
HCACU
$16.2M 0.02%
+1,620,000
New +$16.2M
GEO icon
553
The GEO Group
GEO
$4.03B
$16.1M 0.02%
1,000,000
+325,000
+48% +$5.42M
PAX icon
554
Patria Investments
PAX
$1.81B
$15.9M 0.02%
1,000,000
-293,901
-23% -$4.4M
HII icon
555
Huntington Ingalls Industries
HII
$12.7B
$15.9M 0.02%
46,629
+4,700
+11% +$1.46M
FTV icon
556
Fortive
FTV
$18.4B
$15.8M 0.02%
286,782
-21,200
-7% -$1.1M
VHCPU
557
Vine Hill Capital Investment Corp II Units
VHCPU
$179M
$15.8M 0.02%
+1,575,000
New +$15.8M
GPN icon
558
Global Payments
GPN
$24B
$15.8M 0.02%
203,660
-10,200
-5% -$821K
KHC icon
559
Kraft Heinz
KHC
$29.6B
$15.7M 0.02%
647,432
+168,900
+35% +$4.2M
HLNE icon
560
Hamilton Lane
HLNE
$5.43B
$15.7M 0.02%
+116,740
New +$14.7M
KYTX icon
561
Kyverna Therapeutics
KYTX
$471M
$15.7M 0.02%
+1,666,666
New +$12.4M
IFF icon
562
International Flavors & Fragrances
IFF
$21.6B
$15.6M 0.02%
231,200
-2,100
-0.9% -$136K
DNMX
563
Dynamix Corp III
DNMX
$15.6M 0.02%
+1,575,000
New +$15.6M
MKC icon
564
McCormick & Company Non-Voting
MKC
$14.1B
$15.6M 0.02%
228,630
-111,700
-33% -$7.42M
GPC icon
565
Genuine Parts
GPC
$18.3B
$15.4M 0.02%
125,600
-1,000
-0.8% -$129K
DFTX
566
Definium Therapeutics
DFTX
$6.12B
$15.4M 0.02%
1,150,000
+850,000
+283% +$10.5M
KRSP
567
Rice Acquisition Corporation 3
KRSP
$481M
$15.4M 0.02%
+1,500,000
New +$15.5M
WAB icon
568
Wabtec
WAB
$49.9B
$15.3M 0.02%
71,586
-34,300
-32% -$7.05M
NE icon
569
Noble Corp
NE
$6.5B
$15.1M 0.02%
535,000
-15,000
-3% -$443K
TTD icon
570
Trade Desk
TTD
$8.31B
$15.1M 0.02%
397,500
-8,200
-2% -$363K
BKR icon
571
Baker Hughes
BKR
$62.3B
$15.1M 0.02%
330,902
-86,600
-21% -$4.11M
L icon
572
Loews
L
$23.7B
$15.1M 0.02%
143,000
+13,200
+10% +$1.36M
EVAC
573
EQV Ventures Acquisition Corp II
EVAC
$15M 0.02%
1,500,000
– –
DOW icon
574
Dow Inc
DOW
$21.9B
$15M 0.02%
641,700
-3,600
-0.6% -$82.8K
CDNL
575
Cardinal Infrastructure Group
CDNL
$1.25B
$15M 0.02%
+620,000
New +$15.3M
21 22
23
24 25

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.