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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SILA
526
DELISTED
Sila Realty Trust
SILA
$18M 0.03%
771,571
+193,466
+33% +$4.55M
HBAN icon
527
Huntington Bancshares
HBAN
$35.1B
$18M 0.03%
1,034,950
+76,415
+8% +$1.25M
LVS icon
528
Las Vegas Sands
LVS
$29.9B
$17.9M 0.03%
274,700
-6,500
-2% -$398K
WST icon
529
West Pharmaceutical
WST
$24.5B
$17.9M 0.03%
64,907
+9,400
+17% +$2.57M
VACI
530
Viking Acquisition Corp I
VACI
$311M
$17.8M 0.03%
+1,800,000
New +$17.9M
DOCS icon
531
Doximity
DOCS
$3.77B
$17.7M 0.03%
+400,000
New +$22.5M
KNX icon
532
Knight Transportation
KNX
$11.3B
$17.6M 0.03%
337,506
-87,850
-21% -$4.12M
TYL icon
533
Tyler Technologies
TYL
$12.5B
$17.6M 0.03%
38,800
-600
-2% -$286K
SBXE.U
534
SilverBox Corp V Units
SBXE.U
$17.6M 0.03%
+1,750,000
New +$17.6M
SEM
535
DELISTED
Select Medical
SEM
$17.6M 0.03%
+1,185,399
New +$16.8M
REPL icon
536
Replimune Group
REPL
$1.08B
$17.6M 0.03%
+1,807,368
New +$15.4M
STZ icon
537
Constellation Brands
STZ
$22.6B
$17.6M 0.03%
127,267
-2,700
-2% -$370K
BBOT
538
BridgeBio Oncology
BBOT
$703M
$17.5M 0.03%
1,400,000
-87,621
-6% -$1.06M
ZYME icon
539
Zymeworks
ZYME
$1.7B
$17.5M 0.03%
663,546
+99,546
+18% +$2.17M
AMCR icon
540
Amcor
AMCR
$21.8B
$17.4M 0.03%
416,798
-223,003
-35% -$9.2M
KEY icon
541
KeyCorp
KEY
$24.3B
$17.3M 0.03%
839,669
-9,800
-1% -$182K
IAG icon
542
IAMGOLD
IAG
$9.27B
$17.3M 0.03%
1,050,000
+650,000
+163% +$9.16M
NTRS icon
543
Northern Trust
NTRS
$33.7B
$17.2M 0.03%
125,700
-18,400
-13% -$2.42M
UAL icon
544
United Airlines
UAL
$41.9B
$17M 0.03%
152,309
-347,428
-70% -$35.1M
SHO icon
545
Sunstone Hotel Investors
SHO
$2.1B
$17M 0.03%
1,900,000
+865,000
+84% +$7.93M
DBRG icon
546
DigitalBridge
DBRG
$2.95B
$16.9M 0.03%
+1,100,000
New +$13.2M
UDR icon
547
UDR
UDR
$12.3B
$16.8M 0.03%
456,973
+57,473
+14% +$2.04M
NTAP icon
548
NetApp
NTAP
$37.6B
$16.6M 0.03%
155,200
-2,000
-1% -$228K
MC icon
549
Moelis & Co
MC
$4.98B
$16.5M 0.03%
+239,900
New +$16M
IT icon
550
Gartner
IT
$11.7B
$16.4M 0.02%
65,100
-3,800
-6% -$915K
20 21
22
23 24

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.