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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NVO
426
Novo Nordisk
NVO
$203B
$24.2M 0.04%
+475,000
New +$24.3M
EFX icon
427
Equifax
EFX
$20.7B
$24M 0.04%
110,500
-2,200
-2% -$482K
OMC icon
428
Omnicom Group
OMC
$22.6B
$23.9M 0.04%
296,465
+291,138
+5,465% +$22.2M
CMPX icon
429
Compass Therapeutics
CMPX
$358M
$23.8M 0.04%
4,436,500
-750,000
-14% -$3.46M
FOLD
430
DELISTED
Amicus Therapeutics
FOLD
$23.5M 0.04%
+1,650,000
New +$16.2M
O icon
431
Realty Income
O
$58.2B
$23.5M 0.04%
416,500
-344,900
-45% -$20M
SIGI icon
432
Selective Insurance
SIGI
$5.77B
$23.4M 0.04%
280,000
+65,000
+30% +$5.22M
MDU icon
433
MDU Resources
MDU
$4.34B
$23.4M 0.04%
1,200,000
+200,000
+20% +$3.94M
SAFT icon
434
Safety Insurance
SAFT
$1.52B
$23.4M 0.04%
300,000
+51,400
+21% +$3.8M
BMY icon
435
Bristol-Myers Squibb
BMY
$131B
$23.4M 0.04%
433,169
-146,892
-25% -$7.07M
BFS
436
Saul Centers
BFS
$829M
$23.3M 0.04%
740,000
+50,767
+7% +$1.56M
CF icon
437
CF Industries
CF
$17.9B
$23.3M 0.04%
300,822
+258,400
+609% +$21.2M
QRVO icon
438
Qorvo
QRVO
$8.41B
$23.2M 0.04%
+275,000
New +$24.3M
SPG icon
439
Simon Property Group
SPG
$71.9B
$23.2M 0.04%
125,163
+78,300
+167% +$14.2M
FIX icon
440
Comfort Systems
FIX
$60.3B
$23.1M 0.04%
+24,800
New +$22.9M
STTK icon
441
Shattuck Labs
STTK
$684M
$23M 0.03%
6,306,127
– –
ALB icon
442
Albemarle
ALB
$14.8B
$22.8M 0.03%
161,279
+129,100
+401% +$14.7M
ES icon
443
Eversource Energy
ES
$27.1B
$22.8M 0.03%
338,734
-936,600
-73% -$65.8M
WSC icon
444
WillScot Mobile Mini Holdings
WSC
$4.67B
$22.8M 0.03%
1,208,260
-713,038
-37% -$14.4M
KMI icon
445
Kinder Morgan
KMI
$69.7B
$22.7M 0.03%
827,454
+357,300
+76% +$9.65M
CNP icon
446
CenterPoint Energy
CNP
$26.8B
$22.6M 0.03%
589,438
-4,900
-0.8% -$191K
VICI icon
447
VICI Properties
VICI
$29.2B
$22.5M 0.03%
799,900
+104,100
+15% +$3.09M
SBRA icon
448
Sabra Healthcare REIT
SBRA
$5.34B
$22.4M 0.03%
1,185,000
+550,000
+87% +$10.2M
GIS icon
449
General Mills
GIS
$19.3B
$22.4M 0.03%
481,596
-5,200
-1% -$247K
LLYVK icon
450
Liberty Live Group Series C
LLYVK
$9.54B
$22.4M 0.03%
268,816
+15,000
+6% +$1.29M
16 17
18
19 20

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.