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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CRANU
401
Crane Harbor Acquisition Corp II Units
CRANU
$27.2M 0.04%
+2,700,000
New +$27.1M
KBONU
402
Karbon Capital Partners Corp Units
KBONU
$27.2M 0.04%
+2,700,000
New +$27.2M
ODFL icon
403
Old Dominion Freight Line
ODFL
$44B
$26.9M 0.04%
171,687
-19,100
-10% -$2.74M
AMP icon
404
Ameriprise Financial
AMP
$49.5B
$26.9M 0.04%
54,868
+10,100
+23% +$4.79M
DELL icon
405
Dell
DELL
$283B
$26.7M 0.04%
212,100
+16,100
+8% +$2.27M
F icon
406
Ford
F
$55B
$26.7M 0.04%
2,033,200
+474,600
+30% +$6.12M
AURA icon
407
Aura Biosciences
AURA
$799M
$26.6M 0.04%
4,881,125
– –
KEYS icon
408
Keysight
KEYS
$57.6B
$26.4M 0.04%
130,135
-1,500
-1% -$278K
EQR icon
409
Equity Residential
EQR
$25B
$26.4M 0.04%
418,515
+107,839
+35% +$6.62M
IBKR icon
410
Interactive Brokers
IBKR
$38.8B
$25.9M 0.04%
402,100
-3,200
-0.8% -$214K
CSGP icon
411
CoStar Group
CSGP
$12B
$25.7M 0.04%
382,600
-3,100
-0.8% -$220K
BJ icon
412
BJs Wholesale Club
BJ
$12.4B
$25.7M 0.04%
+285,000
New +$26.2M
FSLR icon
413
First Solar
FSLR
$26.2B
$25.3M 0.04%
96,900
-700
-0.7% -$177K
STLD icon
414
Steel Dynamics
STLD
$37.5B
$25.2M 0.04%
148,900
-82,100
-36% -$13M
SNDK
415
Sandisk
SNDK
$186B
$25.1M 0.04%
+105,699
New +$21.2M
ADM icon
416
Archer Daniels Midland
ADM
$37.4B
$24.9M 0.04%
433,892
-3,500
-0.8% -$209K
VRSK icon
417
Verisk Analytics
VRSK
$24.7B
$24.8M 0.04%
110,800
+3,400
+3% +$767K
BWA icon
418
BorgWarner
BWA
$13.5B
$24.8M 0.04%
550,000
+217,000
+65% +$9.5M
TIC
419
TIC Solutions Inc
TIC
$1.92B
$24.7M 0.04%
2,445,000
+1,834,219
+300% +$20.4M
EME icon
420
Emcor
EME
$35.7B
$24.7M 0.04%
40,400
-300
-0.7% -$194K
VRDN icon
421
Viridian Therapeutics
VRDN
$2.49B
$24.6M 0.04%
790,018
-430,110
-35% -$11.8M
ARES icon
422
Ares Management
ARES
$31.2B
$24.6M 0.04%
152,000
+6,900
+5% +$1.07M
KMPR icon
423
Kemper
KMPR
$1.76B
$24.3M 0.04%
+600,000
New +$25.7M
HUM icon
424
Humana
HUM
$44.1B
$24.2M 0.04%
94,610
-14,900
-14% -$3.91M
SSD icon
425
Simpson Manufacturing
SSD
$7.96B
$24.2M 0.04%
150,000
-25,000
-14% -$4.23M
15 16
17
18 19

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.