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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
STT icon
351
State Street
STT
$50.8B
$32.5M 0.05%
252,132
-6,100
-2% -$730K
CIVI
352
DELISTED
Civitas Resources
CIVI
$32.5M 0.05%
1,200,000
+730,000
+155% +$21.1M
WDAY icon
353
Workday
WDAY
$42B
$32.4M 0.05%
150,900
+4,300
+3% +$977K
XYZ
354
Block Inc
XYZ
$47.5B
$32.1M 0.05%
493,400
+58,100
+13% +$4.01M
MGTX icon
355
MeiraGTx Holdings
MGTX
$1.18B
$31.8M 0.05%
4,000,000
-184,578
-4% -$1.53M
ACGL icon
356
Arch Capital
ACGL
$33.9B
$31.3M 0.05%
326,000
+270,732
+490% +$24.8M
FIS icon
357
Fidelity National Information Services
FIS
$22.1B
$31.1M 0.05%
467,378
+1,800
+0.4% +$119K
CNI icon
358
Canadian National Railway
CNI
$76.5B
$30.9M 0.05%
+312,500
New +$30M
DRUG
359
Bright Minds Biosciences
DRUG
$793M
$30.9M 0.05%
395,743
– –
ROK icon
360
Rockwell Automation
ROK
$49.1B
$30.8M 0.05%
79,225
-59,793
-43% -$22.5M
EXR icon
361
Extra Space Storage
EXR
$31.6B
$30.8M 0.05%
236,600
-1,600
-0.7% -$218K
XENE icon
362
Xenon Pharmaceuticals
XENE
$6.24B
$30.7M 0.05%
685,100
-150,000
-18% -$6.3M
AMAL icon
363
Amalgamated Financial
AMAL
$1.5B
$30.6M 0.05%
953,859
+120,483
+14% +$3.5M
EPRT icon
364
Essential Properties Realty Trust
EPRT
$6.62B
$30.5M 0.05%
1,030,000
-5,000
-0.5% -$152K
GTM
365
ZoomInfo Technologies
GTM
$1.21B
$30.5M 0.05%
3,000,000
+250,000
+9% +$2.57M
FISI icon
366
Financial Institutions
FISI
$827M
$30.3M 0.05%
972,043
+160,825
+20% +$4.74M
YUM icon
367
Yum! Brands
YUM
$41.6B
$30.3M 0.05%
200,202
+28,500
+17% +$4.22M
BCSS
368
Bain Capital GSS Investment Corp
BCSS
$596M
$30.2M 0.05%
+3,000,000
New +$30.2M
BBY icon
369
Best Buy
BBY
$16.9B
$30.1M 0.05%
450,400
+422,500
+1,514% +$32.2M
MNRO icon
370
Monro
MNRO
$388M
$30.1M 0.05%
1,500,000
-722,000
-32% -$13.3M
CCL icon
371
Carnival Corporation Ltd
CCL
$39.4B
$29.9M 0.05%
980,300
+113,900
+13% +$3.18M
GRMN
372
Garmin
GRMN
$58.2B
$29.9M 0.05%
147,570
-1,400
-0.9% -$304K
SGI
373
Somnigroup International
SGI
$13.6B
$29.7M 0.05%
333,000
-71,000
-18% -$6.2M
BXP icon
374
Boston Properties
BXP
$11B
$29.7M 0.04%
440,012
+66,094
+18% +$4.7M
B
375
Barrick Mining
B
$69.3B
$29.6M 0.04%
680,000
-570,000
-46% -$21.4M
13 14
15
16 17

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.