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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CTSH icon
326
Cognizant
CTSH
$25.6B
$36.2M 0.05%
435,750
-8,900
-2% -$666K
TRGP icon
327
Targa Resources
TRGP
$57.6B
$35.8M 0.05%
193,800
-2,100
-1% -$354K
SHW icon
328
Sherwin-Williams
SHW
$88.2B
$35.7M 0.05%
110,306
-9,600
-8% -$3.21M
ULTA icon
329
Ulta Beauty
ULTA
$23.2B
$35.4M 0.05%
58,452
-2,500
-4% -$1.37M
IDXX icon
330
Idexx Laboratories
IDXX
$46.5B
$35.2M 0.05%
52,047
+16,377
+46% +$11.2M
CCI icon
331
Crown Castle
CCI
$32.7B
$34.9M 0.05%
393,160
-28,300
-7% -$2.6M
HAS icon
332
Hasbro
HAS
$12.9B
$34.7M 0.05%
423,372
-197,900
-32% -$15.5M
MTSI icon
333
MACOM Technology Solutions
MTSI
$23B
$34.7M 0.05%
+202,500
New +$32.1M
ALL icon
334
Allstate
ALL
$70.8B
$34.6M 0.05%
166,219
-159,400
-49% -$32.6M
SIMO icon
335
Silicon Motion
SIMO
$9.07B
$34.5M 0.05%
371,662
-74,504
-17% -$6.84M
KDP icon
336
Keurig Dr Pepper
KDP
$41.3B
$34.4M 0.05%
1,226,500
-275,200
-18% -$7.56M
CMG icon
337
Chipotle Mexican Grill
CMG
$42.7B
$34.3M 0.05%
927,750
-292,900
-24% -$10.6M
MSCI icon
338
MSCI
MSCI
$41.2B
$34.3M 0.05%
59,800
-4,600
-7% -$2.58M
RDNT icon
339
RadNet
RDNT
$5.36B
$34M 0.05%
476,626
+247,356
+108% +$19.1M
NPB
340
Northpointe Bancshares
NPB
$592M
$33.9M 0.05%
2,018,214
+224,110
+12% +$3.79M
NUE icon
341
Nucor
NUE
$61.9B
$33.7M 0.05%
206,600
-2,400
-1% -$361K
AMLX icon
342
Amylyx Pharmaceuticals
AMLX
$2.69B
$33.5M 0.05%
2,777,055
-4,039,773
-59% -$54.9M
KYMR icon
343
Kymera Therapeutics
KYMR
$8.75B
$33.5M 0.05%
430,000
+192,000
+81% +$13M
SHEL icon
344
Shell
SHEL
$248B
$33.4M 0.05%
455,000
-30,000
-6% -$2.21M
GFS icon
345
GlobalFoundries
GFS
$27.6B
$33.2M 0.05%
950,000
+300,000
+46% +$10.7M
DDOG icon
346
Datadog
DDOG
$81.6B
$33.2M 0.05%
243,800
-20,500
-8% -$3.24M
RELY icon
347
Remitly
RELY
$5.46B
$33.1M 0.05%
2,400,000
+165,000
+7% +$2.4M
BLDR icon
348
Builders FirstSource
BLDR
$7.8B
$33.1M 0.05%
321,800
+170,068
+112% +$19.1M
TFC icon
349
Truist Financial
TFC
$64.2B
$32.8M 0.05%
666,164
-203,400
-23% -$9.37M
FISV
350
Fiserv Inc
FISV
$28.9B
$32.6M 0.05%
485,281
-8,800
-2% -$737K
12 13
14
15 16

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.