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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PANW icon
276
Palo Alto Networks
PANW
$293B
$45.8M 0.07%
248,776
+155,897
+168% +$31.5M
AXTA icon
277
Axalta
AXTA
$8.03B
$45.6M 0.07%
1,410,569
-212,051
-13% -$6.22M
AHR icon
278
American Healthcare REIT
AHR
$10.5B
$45.2M 0.07%
960,000
-65,000
-6% -$3.01M
PWP icon
279
Perella Weinberg Partners
PWP
$1.26B
$44.6M 0.07%
2,580,571
+708,052
+38% +$13.2M
WDC icon
280
Western Digital
WDC
$156B
$44.6M 0.07%
258,637
+17,800
+7% +$2.7M
PWR icon
281
Quanta Services
PWR
$100B
$44.5M 0.07%
105,524
-6,200
-6% -$2.72M
JHX icon
282
James Hardie Industries
JHX
$16.2B
$44.4M 0.07%
2,140,375
+173,306
+9% +$3.48M
AFG icon
283
American Financial Group
AFG
$12.2B
$43.8M 0.07%
+320,694
New +$44M
IP icon
284
International Paper
IP
$21.5B
$43.8M 0.07%
1,112,692
-258,000
-19% -$10.6M
UMBF icon
285
UMB Financial
UMBF
$11B
$43.7M 0.07%
380,211
+114,279
+43% +$12.9M
ETOR
286
eToro Group
ETOR
$2.82B
$43.6M 0.07%
1,240,339
+401,697
+48% +$15.5M
ZBRA icon
287
Zebra Technologies
ZBRA
$17.2B
$43.5M 0.07%
179,003
+127,818
+250% +$34.2M
FRT icon
288
Federal Realty Investment Trust
FRT
$10.2B
$43.3M 0.07%
429,129
+40,996
+11% +$4.04M
WMB icon
289
Williams Companies
WMB
$87.8B
$42.9M 0.06%
713,699
+223,200
+46% +$13.5M
MCB icon
290
Metropolitan Bank Holding Corp
MCB
$1.15B
$42.7M 0.06%
559,479
+299,061
+115% +$22.2M
ABNB icon
291
Airbnb
ABNB
$90B
$42.5M 0.06%
313,000
-37,600
-11% -$4.68M
VLO icon
292
Valero Energy
VLO
$87.2B
$42.4M 0.06%
260,400
+47,600
+22% +$8.06M
MNPR icon
293
Monopar Therapeutics
MNPR
$805M
$41.8M 0.06%
639,467
-19,728
-3% -$1.61M
NXPI icon
294
NXP Semiconductors
NXPI
$58.4B
$41.7M 0.06%
192,208
-37,300
-16% -$8M
AIG icon
295
American International
AIG
$42.4B
$41.7M 0.06%
487,138
-265,138
-35% -$21.2M
AJG icon
296
Arthur J. Gallagher & Co
AJG
$64.5B
$41.4M 0.06%
159,803
-133,300
-45% -$35.3M
DAY
297
DELISTED
Dayforce
DAY
$41.1M 0.06%
594,500
+449,100
+309% +$30.9M
EXE
298
Expand Energy Corp
EXE
$21.3B
$40.8M 0.06%
370,000
-306,800
-45% -$34M
SHAK icon
299
Shake Shack
SHAK
$2.83B
$40.8M 0.06%
+503,000
New +$44.3M
DAL icon
300
Delta Air Lines
DAL
$60.5B
$40.6M 0.06%
585,611
-1,061,618
-64% -$66.3M
10 11
12
13 14

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.