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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CUZ icon
251
Cousins Properties
CUZ
$4.91B
$49.9M 0.08%
1,935,048
+15,747
+0.8% +$409K
NRG icon
252
NRG Energy
NRG
$25.1B
$49.9M 0.08%
313,052
+137,000
+78% +$22.7M
PNC icon
253
PNC Financial Services
PNC
$101B
$49.8M 0.08%
238,468
-44,600
-16% -$8.61M
IDA icon
254
Idacorp
IDA
$8.16B
$49.7M 0.08%
392,500
+165,000
+73% +$21.5M
LHX icon
255
L3Harris
LHX
$53.9B
$49.6M 0.08%
169,059
-1,100
-0.6% -$318K
ADSK icon
256
Autodesk
ADSK
$51.2B
$49.5M 0.07%
167,289
-2,300
-1% -$696K
NOC icon
257
Northrop Grumman
NOC
$80.7B
$49.5M 0.07%
86,748
-30,676
-26% -$17.8M
MNST icon
258
Monster Beverage
MNST
$92.1B
$49.4M 0.07%
643,922
-5,000
-0.8% -$358K
NAMS icon
259
NewAmsterdam Pharma
NAMS
$3.23B
$49.3M 0.07%
1,406,631
-1,170,000
-45% -$42.6M
DRI icon
260
Darden Restaurants
DRI
$24.1B
$49M 0.07%
266,004
+159,500
+150% +$29.1M
IEX icon
261
IDEX
IEX
$17.2B
$48.7M 0.07%
273,476
+29,000
+12% +$4.96M
CTAS icon
262
Cintas
CTAS
$80.9B
$48.6M 0.07%
258,400
-60,318
-19% -$11.4M
TRMB icon
263
Trimble
TRMB
$13.7B
$48.5M 0.07%
618,822
-102,812
-14% -$8.19M
APD icon
264
Air Products & Chemicals
APD
$66.8B
$48.4M 0.07%
195,940
-41,400
-17% -$10.5M
ALH
265
Alliance Laundry Holdings
ALH
$5.47B
$48.2M 0.07%
+2,370,244
New +$57M
GH icon
266
Guardant Health
GH
$21.2B
$47.5M 0.07%
464,905
+312,783
+206% +$28M
HCA icon
267
HCA Healthcare
HCA
$88.6B
$47.5M 0.07%
101,700
+36,424
+56% +$16.9M
MET icon
268
MetLife
MET
$64.4B
$47.3M 0.07%
599,626
+366,100
+157% +$29M
AFL icon
269
Aflac
AFL
$64.5B
$47M 0.07%
425,874
+57,700
+16% +$6.36M
PEN icon
270
Penumbra
PEN
$12.8B
$46.6M 0.07%
150,000
+12,210
+9% +$3.37M
COIN icon
271
Coinbase
COIN
$38.3B
$46.6M 0.07%
206,000
+300
+0.1% +$89.4K
ZION icon
272
Zions Bancorporation
ZION
$10.3B
$46.4M 0.07%
792,386
+187,386
+31% +$10.2M
CR icon
273
Crane Co
CR
$12.6B
$46.3M 0.07%
251,000
+74,000
+42% +$13.7M
STX icon
274
Seagate
STX
$193B
$46M 0.07%
167,201
+87,100
+109% +$22.6M
XIFR
275
XPLR Infrastructure LP
XIFR
$1.08B
$46M 0.07%
4,600,000
+3,900,000
+557% +$37.8M
9 10
11
12 13

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.