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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
JBL icon
226
Jabil
JBL
$36.3B
$56.3M 0.09%
246,791
+52,800
+27% +$11.3M
OCUL icon
227
Ocular Therapeutix
OCUL
$1.89B
$56.1M 0.09%
4,625,050
+620,700
+16% +$7.54M
NI icon
228
NiSource
NI
$20.6B
$55.8M 0.08%
1,335,862
+7,200
+0.5% +$308K
ETR icon
229
Entergy
ETR
$49.7B
$55.8M 0.08%
603,204
-363,200
-38% -$34.4M
MMM icon
230
3M
MMM
$92.9B
$55.5M 0.08%
346,519
+70,397
+25% +$11.5M
TDY icon
231
Teledyne Technologies
TDY
$31.7B
$55.4M 0.08%
108,392
+65,750
+154% +$34.6M
AWI icon
232
Armstrong World Industries
AWI
$7.81B
$55M 0.08%
288,000
-45,000
-14% -$8.59M
ROP icon
233
Roper Technologies
ROP
$38.7B
$54.9M 0.08%
123,331
-20,154
-14% -$9.33M
RBA icon
234
RB Global
RBA
$17.5B
$54.9M 0.08%
533,621
-562,920
-51% -$57.2M
XYL icon
235
Xylem
XYL
$28.3B
$54.7M 0.08%
401,793
+230,200
+134% +$33.1M
IRM icon
236
Iron Mountain
IRM
$36.7B
$54.5M 0.08%
656,852
+103,432
+19% +$9.68M
XEL icon
237
Xcel Energy
XEL
$48.2B
$54.2M 0.08%
734,191
+195,749
+36% +$15.4M
APO icon
238
Apollo Global Management
APO
$74B
$54M 0.08%
373,200
-20,200
-5% -$2.68M
RIO icon
239
Rio Tinto
RIO
$163B
$54M 0.08%
674,602
+50,000
+8% +$3.6M
CVNA icon
240
Carvana
CVNA
$76.3B
$53.9M 0.08%
+638,500
New +$47.5M
BBT
241
Beacon Financial Corp
BBT
$2.67B
$53.7M 0.08%
2,036,828
+417,632
+26% +$10.6M
FBIN icon
242
Fortune Brands Innovations
FBIN
$6.14B
$52.8M 0.08%
1,056,000
+481,000
+84% +$24.1M
SLB icon
243
SLB Ltd
SLB
$77.4B
$52.7M 0.08%
1,373,667
+160,400
+13% +$5.81M
NWE icon
244
NorthWestern Energy
NWE
$4.3B
$52.4M 0.08%
+812,500
New +$51.4M
INSM icon
245
Insmed
INSM
$28.4B
$52.2M 0.08%
300,000
-952,503
-76% -$174M
TXNM
246
TXNM Energy Inc
TXNM
$5.91B
$52M 0.08%
883,320
-549,955
-38% -$31.7M
BIIB icon
247
Biogen
BIIB
$30.1B
$51.8M 0.08%
294,357
-37,775
-11% -$6.17M
AZO icon
248
AutoZone
AZO
$50B
$50.9M 0.08%
15,015
-7,133
-32% -$26.9M
HUBS icon
249
HubSpot
HUBS
$10.1B
$50.2M 0.08%
125,000
– –
MRX
250
Marex Group Limited Ordinary Shares
MRX
$4.52B
$50.1M 0.08%
1,305,455
-27,045
-2% -$920K
8 9
10
11 12

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.