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Immunotherapy & Oncology

Cancer treatment has moved from poisoning dividing cells towards directing the immune system at the tumour, and towards drugs that carry their payload only to cancerous tissue. It absorbs more drug development spending than any other area.

388 stocks

#	Name	Holding	Trade Value	Theme Stocks	% of Portfolio	Status
1	Vanguard Group Malvern, Pennsylvania	$51.2B	+$685M	59	4.5%	Increased
2	State Street Boston, Massachusetts	$47.9B	+$462M	51	5.33%	Increased
3	Fidelity Investments Boston, Massachusetts	$32.7B	-$609M	47	4.62%	Reduced
4	Capital World Investors Los Angeles, California	$29.4B	-$1.16B	13	8.26%	Reduced
5	BlackRock Institutional Trust San Francisco, California	$27.6B	-$9.34M	54	4.87%	Reduced
6	Wellington Management Group Boston, Massachusetts	$27.5B	-$772M	27	7.92%	Reduced
7	Capital Research Global Investors Los Angeles, California	$26.1B	-$910M	10	9.67%	Reduced
8	T. Rowe Price Associates Baltimore, Maryland	$19.9B	-$270M	30	4.56%	Reduced
9	Bank of New York Mellon New York	$17.9B	-$687M	52	4.97%	Reduced
10	BNP Paribas Financial Markets Paris, France	$17.8B	-$1.84B	47	12.95%	Reduced
11	Northern Trust Chicago, Illinois	$15.6B	-$68.4M	58	5.02%	Reduced
12	JP Morgan Chase New York	$14.3B	-$685M	34	4.06%	Reduced
13	BlackRock Fund Advisors San Francisco, California	$13.3B	+$310M	54	4.04%	Increased
14	Franklin Resources San Mateo, California	$12.1B	-$783M	29	5.91%	Reduced
15	Dodge & Cox San Francisco, California	$11.4B	-$203M	8	11.92%	Reduced
16	Invesco Atlanta, Georgia	$11B	+$138M	32	4.37%	Increased
17	Primecap Management Pasadena, California	$8.94B	-$43.5M	9	10.74%	Reduced
18	Ameriprise Minneapolis, Minnesota	$8.76B	+$640M	34	5.31%	Increased
19	Bank of America Charlotte, North Carolina	$8.67B	+$200M	59	3.12%	Increased
20	BlackRock Group London, United Kingdom	$8.28B	-$622M	29	5.34%	Reduced
21	Norges Bank Oslo, Norway	$7.84B	-$578M	21	4.52%	Reduced
22	Geode Capital Management Boston, Massachusetts	$7.69B	+$348M	58	5.33%	Increased
23	Massachusetts Financial Services Boston, Massachusetts	$7.43B	-$385M	10	4.17%	Reduced
24	State Farm Mutual Automobile Insurance Bloomington, Illinois	$7.37B	+$489K	8	11.76%	Increased
25	Wells Fargo San Francisco, California	$7.09B	+$431M	49	3.08%	Increased