|
51
|
ClearBridge Investments
New York
|
$380M
|
-$54M
|
4
|
0.3%
|
Reduced
|
|
|
52
|
Paradigm Biocapital Advisors
New York
|
$379M
|
-$217M
|
2
|
12.81%
|
Reduced
|
|
|
53
|
Balyasny Asset Management
Chicago,
Illinois
|
$373M
|
-$22.7M
|
20
|
0.61%
|
Reduced
|
|
|
54
|
Redmile Group
San Francisco,
California
|
$351M
|
-$35.5M
|
11
|
20.69%
|
Reduced
|
|
|
55
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$351M
|
-$9.63M
|
3
|
7.71%
|
Reduced
|
|
|
56
|
Pictet Asset Management
Carouge,
Switzerland
|
$347M
|
+$31.6M
|
16
|
0.38%
|
Increased
|
|
|
57
|
Armistice Capital
New York
|
$344M
|
-$10.9M
|
9
|
5.5%
|
Reduced
|
|
|
58
|
Westfield Capital Management
Boston,
Massachusetts
|
$329M
|
+$17.6M
|
2
|
1.48%
|
Increased
|
|
|
59
|
Baker Bros. Advisors
New York
|
$315M
|
+$42M
|
13
|
3.26%
|
Increased
|
|
|
60
|
Envestnet Asset Management
Chicago,
Illinois
|
$309M
|
-$4.63M
|
19
|
0.1%
|
Reduced
|
|
|
61
|
|
$304M
|
-$17.6M
|
25
|
0.08%
|
Reduced
|
|
|
62
|
Nuveen
Charlotte,
North Carolina
|
$296M
|
-$24.9M
|
52
|
0.08%
|
Reduced
|
|
|
63
|
EARNEST Partners
Atlanta,
Georgia
|
$286M
|
-$4.81M
|
2
|
1.25%
|
Reduced
|
|
|
64
|
Sands Capital Management
Arlington,
Virginia
|
$284M
|
-$12M
|
1
|
0.86%
|
Reduced
|
|
|
65
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$274M
|
+$41M
|
66
|
0.06%
|
Increased
|
|
|
66
|
Marshall Wace
London,
United Kingdom
|
$273M
|
-$117M
|
33
|
0.33%
|
Reduced
|
|
|
67
|
Sumitomo Mitsui Trust Group
Minato-Ku, Tokyo,
Japan
|
$272M
|
-$9.58M
|
7
|
0.19%
|
Reduced
|
|
|
68
|
Ameriprise
Minneapolis,
Minnesota
|
$272M
|
-$36.8M
|
27
|
0.07%
|
Reduced
|
|
|
69
|
SR One Capital Management
Wayne,
Pennsylvania
|
$265M
|
+$1.84M
|
4
|
53.18%
|
Increased
|
|
|
70
|
Cullen Capital Management
New York
|
$259M
|
-$70.2M
|
1
|
2.82%
|
Reduced
|
|
|
71
|
Fidelity International
Hamilton,
Bermuda
|
$258M
|
+$136M
|
6
|
0.23%
|
Increased
|
|
|
72
|
Suvretta Capital Management
New York
|
$251M
|
-$41.9M
|
6
|
8.03%
|
Reduced
|
|
|
73
|
Alkeon Capital Management
New York
|
$246M
|
+$30M
|
2
|
0.42%
|
Increased
|
|
|
74
|
Woodline Partners
San Francisco,
California
|
$244M
|
+$2.93M
|
24
|
2.06%
|
Increased
|
|
|
75
|
EcoR1 Capital
San Francisco,
California
|
$243M
|
-$380M
|
13
|
8.31%
|
Reduced
|
|