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Xencor

193 hedge funds and large institutions have $647M invested in Xencor in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 93 increasing their positions, 37 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

151% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 37

3.82% more ownership

Funds ownership: 111.77%115.59% (+3.8%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

4% less funds holding

Funds holding: 202193 (-9)

23% less capital invested

Capital invested by funds: $838M → $647M (-$191M)

25% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 32

Holders
193
Holders Change
-9
Holders Change %
-4.46%
% of All Funds
2.54%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
24
Increased
93
Reduced
37
Closed
32
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Canada Life
76
Canada Life
Manitoba, Canada
$550K +$20.2K +2,256 +3%
Fidelity Investments
77
Fidelity Investments
Massachusetts
$537K -$74.7K -8,325 -11%
State of Wisconsin Investment Board
78
State of Wisconsin Investment Board
Wisconsin
$515K +$256K +28,537 +77%
SFI
79
Susquehanna Fundamental Investments
Pennsylvania
$504K -$334K -37,208 -37%
Man Group
80
Man Group
United Kingdom
$485K +$554K +61,752 New
IIM
81
INTECH Investment Management
Florida
$482K -$29.7K -3,305 -5%
New York State Teachers Retirement System (NYSTRS)
82
New York State Teachers Retirement System (NYSTRS)
New York
$467K +$897 +100 +0.2%
Renaissance Technologies
83
Renaissance Technologies
New York
$437K -$869K -96,800 -64%
California State Teachers Retirement System (CalSTRS)
84
California State Teachers Retirement System (CalSTRS)
California
$426K -$44.3K -4,937 -8%
Ohio Public Employees Retirement System (OPERS)
85
Ohio Public Employees Retirement System (OPERS)
Ohio
$407K
EGM
86
Engineers Gate Manager
New York
$397K +$454K +50,562 New
II
87
Inspire Investing
Idaho
$386K +$150K +16,709 +52%
CC
88
Centiva Capital
New York
$385K +$439K +48,958 New
Wells Fargo
89
Wells Fargo
California
$363K +$59.9K +6,673 +17%
Franklin Resources
90
Franklin Resources
California
$351K +$20.7K +2,307 +5%
Mirae Asset Global ETFs Holdings
91
Mirae Asset Global ETFs Holdings
Hong Kong
$341K -$7.02K -782 -2%
LTAS
92
Linden Thomas Advisory Services
North Carolina
$334K -$6.48K -722 -2%
SOADOR
93
State of Alaska Department of Revenue
Alaska
$332K +$32.1K +3,574 +9%
MIM
94
MetLife Investment Management
New Jersey
$317K
Deutsche Bank
95
Deutsche Bank
Germany
$310K -$116K -12,947 -25%
JG
96
Jain Global
New York
$306K +$350K +38,981 New
AA
97
ALPS Advisors
Colorado
$302K -$117K -13,060 -25%
Ensign Peak Advisors
98
Ensign Peak Advisors
Utah
$287K
Russell Investments Group
99
Russell Investments Group
United Kingdom
$271K -$2.43K -271 -0.8%
HS
100
HighVista Strategies
Massachusetts
$262K +$12.2K +1,362 +4%

XNCR Hedge Fund Activity: Q2 2025 in Review

193 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q2 2025, worth a combined $647M — down 23% from $838M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of XNCR and 24 opened new positions — a net loss of 8 holders — while 37 trimmed existing stakes and 93 added.

The largest buyer was Royal Bank of Canada, adding an estimated $11.7M. The largest seller was Loomis, Sayles & Company, exiting entirely with an estimated $11.4M sold.

  • 193 institutional investors held Xencor (XNCR) as of Q2 2025, down from 202 in Q1 2025.
  • Funds reported $647M of Xencor stock for Q2 2025, down 23% quarter-over-quarter.
  • 24 funds opened new Xencor positions in Q2 2025 and 32 closed out, a net change of -8 holders.
  • The largest Xencor buyer in Q2 2025 was Royal Bank of Canada, an estimated $11.7M added.
  • The largest Xencor seller in Q2 2025 was Loomis, Sayles & Company, an estimated $11.4M sold.

Based on aggregated 13F filings for Q2 2025.