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206 hedge funds and large institutions have $960M invested in Xencor in 2025 Q3 according to their latest regulatory filings, with 34 funds opening new positions, 56 increasing their positions, 81 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 19

48% more capital invested

Capital invested by funds: $647M → $960M (+$313M)

7% more funds holding

Funds holding: 193206 (+13)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

0.72% less ownership

Funds ownership: 115.59%114.87% (-0.72%)

31% less repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 81

Holders
206
Holders Change
+13
Holders Change %
+6.74%
% of All Funds
2.7%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
34
Increased
56
Reduced
81
Closed
19
Calls
$116K
Puts
Net Calls
+$116K
Net Calls Change
+$116K
Name Holding Trade Value Shares
Change
Change in
Stake
Ameriprise
51
Ameriprise
Minnesota
$1.72M -$1.46M -168,170 -53%
TI
52
Trexquant Investment
Connecticut
$1.6M -$306K -35,310 -21%
N
53
Nuveen
North Carolina
$1.57M
ACM
54
ADAR1 Capital Management
Texas
$1.51M +$374K +43,039 +50%
WG
55
Winton Group
United Kingdom
$1.47M +$297K +34,214 +37%
BNP Paribas Financial Markets
56
BNP Paribas Financial Markets
France
$1.46M +$44.7K +5,154 +4%
HF
57
HRT Financial
New York
$1.46M +$1.08M +124,063 New
YIH
58
Y-Intercept (HK)
Hong Kong
$1.44M +$238K +27,393 +29%
Swiss National Bank
59
Swiss National Bank
Switzerland
$1.35M
SPS
60
Susquehanna Portfolio Strategies
Pennsylvania
$1.25M +$927K +106,855 New
JFG
61
Jefferies Financial Group
New York
$1.17M +$868K +100,000 New
CSS
62
Cubist Systematic Strategies
Connecticut
$1.17M -$2.04M -235,591 -70%
EL
63
Essex LLC
Illinois
$1.17M -$52.9K -6,100 -6%
Los Angeles Capital Management
64
Los Angeles Capital Management
California
$1.16M +$25.1K +2,891 +3%
Manulife (Manufacturers Life Insurance)
65
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.12M -$82.8K -9,543 -9%
SG Americas Securities
66
SG Americas Securities
New York
$1.06M +$785K +90,501 New
Thrivent Financial for Lutherans
67
Thrivent Financial for Lutherans
Minnesota
$1.03M -$292K -33,593 -28%
AQR Capital Management
68
AQR Capital Management
Connecticut
$1.02M -$82.3K -9,483 -10%
TD Asset Management
69
TD Asset Management
Ontario, Canada
$1.01M -$139K -15,986 -16%
Fidelity Investments
70
Fidelity Investments
Massachusetts
$867K +$48.6K +5,603 +8%
AllianceBernstein
71
AllianceBernstein
Tennessee
$846K
Prudential Financial
72
Prudential Financial
New Jersey
$845K +$391 +45 +0.1%
Rafferty Asset Management
73
Rafferty Asset Management
New York
$820K -$180K -20,723 -23%
Canada Life
74
Canada Life
Manitoba, Canada
$808K
WAM
75
Weiss Asset Management
Massachusetts
$777K +$575K +66,273 New

XNCR Hedge Fund Activity: Q3 2025 in Review

206 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q3 2025, worth a combined $960M — up 48% from $647M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new XNCR positions and 19 closed out — a net gain of 15 holders — while 56 added to existing stakes and 81 trimmed.

The largest buyer was RTW Investments, adding an estimated $33.1M. The largest seller was T. Rowe Price Associates, cutting an estimated $17.9M.

  • 206 institutional investors held Xencor (XNCR) as of Q3 2025, up from 193 in Q2 2025.
  • Funds reported $960M of Xencor stock for Q3 2025, up 48% quarter-over-quarter.
  • 34 funds opened new Xencor positions in Q3 2025 and 19 closed out, a net change of +15 holders.
  • The largest Xencor buyer in Q3 2025 was RTW Investments, an estimated $33.1M added.
  • The largest Xencor seller in Q3 2025 was T. Rowe Price Associates, an estimated $17.9M sold.

Based on aggregated 13F filings for Q3 2025.