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Xencor
XNCR

193 hedge funds and large institutions have $647M invested in Xencor in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 93 increasing their positions, 37 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

151% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 37

3.82% more ownership

Funds ownership: 111.77% → 115.59% (+3.8%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

4% less funds holding

Funds holding: 202 → 193 (-9)

23% less capital invested

Capital invested by funds: $838M → $647M (-$191M)

25% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 32

Holders
193
Holders Change
-9
Holders Change %
-4.46%
% of All Funds
2.54%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
24
Increased
93
Reduced
37
Closed
32
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
+$11.7M
2
LGM
Logos Global Management
California
+$11.2M
3
Primecap Management
Primecap Management
California
+$6.88M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$6.51M
5
Barclays
Barclays
United Kingdom
+$4.27M

Top Sellers

Rank Fund Capital Flow
1
Loomis, Sayles & Company
Loomis, Sayles & Company
Massachusetts
-$11.4M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$9.17M
3
FC
Finepoint Capital
Massachusetts
-$6.83M
4
RCM
RA Capital Management
Massachusetts
-$6.12M
5
Invesco
Invesco
Georgia
-$3.94M
Name Holding Trade Value Shares
Change 		Change in
Stake
RPAM
51
Rhenman & Partners Asset Management
Sweden
$1.3M -$269K -30,000 -15%
American Century Companies
52
American Century Companies
Missouri
$1.23M +$150K +16,731 +12%
DA
53
DCF Advisers
Connecticut
$1.1M -$558K -62,167 -31%
N
54
Nuveen
North Carolina
$1.05M -$243K -27,098 -17%
AG
55
Algert Global
California
$1.04M +$1.19M +132,045 New
Verition Fund Management
56
Verition Fund Management
Connecticut
$1.01M +$906K +100,917 +360%
JF
57
Jump Financial
Illinois
$998K +$687K +76,499 +152%
Thrivent Financial for Lutherans
58
Thrivent Financial for Lutherans
Minnesota
$952K +$8.35K +930 +0.8%
BNP Paribas Financial Markets
59
BNP Paribas Financial Markets
France
$935K +$733K +81,640 +219%
Swiss National Bank
60
Swiss National Bank
Switzerland
$906K – – –
EL
61
Essex LLC
Illinois
$833K -$33.2K -3,700 -3%
Manulife (Manufacturers Life Insurance)
62
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$823K +$29.1K +3,243 +3%
TD Asset Management
63
TD Asset Management
Ontario, Canada
$800K – – –
Citigroup
64
Citigroup
New York
$780K -$592K -65,995 -40%
AQR Capital Management
65
AQR Capital Management
Connecticut
$757K +$495K +55,174 +134%
Los Angeles Capital Management
66
Los Angeles Capital Management
California
$753K +$746K +83,143 +654%
YIH
67
Y-Intercept (HK)
Hong Kong
$753K +$414K +46,140 +93%
Susquehanna International Group
68
Susquehanna International Group
Pennsylvania
$732K -$57.9K -6,448 -6%
Acadian Asset Management
69
Acadian Asset Management
Massachusetts
$726K +$831K +92,614 New
WG
70
Winton Group
United Kingdom
$717K +$47.3K +5,271 +6%
Rafferty Asset Management
71
Rafferty Asset Management
New York
$712K +$34.6K +3,858 +4%
ACM
72
ADAR1 Capital Management
Texas
$675K -$2.8M -312,326 -78%
AllianceBernstein
73
AllianceBernstein
Tennessee
$567K – – –
Prudential Financial
74
Prudential Financial
New Jersey
$566K +$33.3K +3,715 +5%
BC
75
Birchview Capital
Vermont
$550K +$395K +44,000 +169%
1 2
3
4 5

XNCR Hedge Fund Activity: Q2 2025 in Review

193 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q2 2025, worth a combined $647M — down 23% from $838M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of XNCR and 24 opened new positions — a net loss of 8 holders — while 37 trimmed existing stakes and 93 added.

The largest buyer was Royal Bank of Canada, adding an estimated $11.7M. The largest seller was Loomis, Sayles & Company, exiting entirely with an estimated $11.4M sold.

  • 193 institutional investors held Xencor (XNCR) as of Q2 2025, down from 202 in Q1 2025.
  • Funds reported $647M of Xencor stock for Q2 2025, down 23% quarter-over-quarter.
  • 24 funds opened new Xencor positions in Q2 2025 and 32 closed out, a net change of -8 holders.
  • The largest Xencor buyer in Q2 2025 was Royal Bank of Canada, an estimated $11.7M added.
  • The largest Xencor seller in Q2 2025 was Loomis, Sayles & Company, an estimated $11.4M sold.

Based on aggregated 13F filings for Q2 2025.