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206 hedge funds and large institutions have $960M invested in Xencor in 2025 Q3 according to their latest regulatory filings, with 34 funds opening new positions, 56 increasing their positions, 81 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 19

48% more capital invested

Capital invested by funds: $647M → $960M (+$313M)

7% more funds holding

Funds holding: 193206 (+13)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

0.72% less ownership

Funds ownership: 115.59%114.87% (-0.72%)

31% less repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 81

Holders
206
Holders Change
+13
Holders Change %
+6.74%
% of All Funds
2.7%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
34
Increased
56
Reduced
81
Closed
19
Calls
$116K
Puts
Net Calls
+$116K
Net Calls Change
+$116K
Name Holding Trade Value Shares
Change
Change in
Stake
PAM
26
Panagora Asset Management
Massachusetts
$7.28M +$1.15M +132,137 +27%
Barclays
27
Barclays
United Kingdom
$7.04M -$469K -54,052 -8%
Aberdeen Group
28
Aberdeen Group
United Kingdom
$6.55M
DTC
29
Deep Track Capital
Connecticut
$6.44M
Acadian Asset Management
30
Acadian Asset Management
Massachusetts
$6.24M +$3.82M +439,588 +475%
Citadel Advisors
31
Citadel Advisors
Florida
$5.64M +$2.26M +260,900 +118%
Hudson Bay Capital Management
32
Hudson Bay Capital Management
Connecticut
$5.4M -$217K -24,997 -5%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$4.99M -$459K -52,890 -11%
JP Morgan Chase
34
JP Morgan Chase
New York
$4.71M +$621K +71,494 +22%
EAM
35
Erste Asset Management
Austria
$4.39M
AG
36
Algert Global
California
$4.23M +$1.98M +228,417 +173%
Royal Bank of Canada
37
Royal Bank of Canada
Ontario, Canada
$4.06M -$8.44M -972,808 -74%
Principal Financial Group
38
Principal Financial Group
Iowa
$4.04M -$72.8K -8,383 -2%
Macquarie Group
39
Macquarie Group
Australia
$3.92M +$1.74M +200,000 +100%
Public Sector Pension Investment Board (PSP Investments)
40
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$3.26M +$309K +35,575 +15%
Invesco
41
Invesco
Georgia
$2.95M +$301K +34,703 +16%
Squarepoint
42
Squarepoint
New York
$2.54M -$1.27M -146,414 -40%
WP
43
Woodline Partners
California
$2.27M -$5.64M -650,179 -77%
Renaissance Technologies
44
Renaissance Technologies
New York
$2.23M +$1.17M +134,789 +242%
DA
45
DCF Advisers
Connecticut
$2.23M +$432K +49,736 +36%
RhumbLine Advisers
46
RhumbLine Advisers
Massachusetts
$2.06M -$4.82K -555 -0.3%
JF
47
Jump Financial
Illinois
$2.06M +$423K +48,769 +38%
American Century Companies
48
American Century Companies
Missouri
$2.03M +$151K +17,409 +11%
UBS AM
49
UBS AM
Illinois
$1.95M -$375K -43,233 -21%
RPAM
50
Rhenman & Partners Asset Management
Sweden
$1.94M

XNCR Hedge Fund Activity: Q3 2025 in Review

206 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q3 2025, worth a combined $960M — up 48% from $647M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new XNCR positions and 19 closed out — a net gain of 15 holders — while 56 added to existing stakes and 81 trimmed.

The largest buyer was RTW Investments, adding an estimated $33.1M. The largest seller was T. Rowe Price Associates, cutting an estimated $17.9M.

  • 206 institutional investors held Xencor (XNCR) as of Q3 2025, up from 193 in Q2 2025.
  • Funds reported $960M of Xencor stock for Q3 2025, up 48% quarter-over-quarter.
  • 34 funds opened new Xencor positions in Q3 2025 and 19 closed out, a net change of +15 holders.
  • The largest Xencor buyer in Q3 2025 was RTW Investments, an estimated $33.1M added.
  • The largest Xencor seller in Q3 2025 was T. Rowe Price Associates, an estimated $17.9M sold.

Based on aggregated 13F filings for Q3 2025.