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Xencor

193 hedge funds and large institutions have $647M invested in Xencor in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 93 increasing their positions, 37 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

151% more repeat investments, than reductions

Existing positions increased: 93 | Existing positions reduced: 37

3.82% more ownership

Funds ownership: 111.77%115.59% (+3.8%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

4% less funds holding

Funds holding: 202193 (-9)

23% less capital invested

Capital invested by funds: $838M → $647M (-$191M)

25% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 32

Holders
193
Holders Change
-9
Holders Change %
-4.46%
% of All Funds
2.54%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
24
Increased
93
Reduced
37
Closed
32
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
26
Two Sigma Advisers
New York
$4.55M +$1.62M +181,000 +45%
Aberdeen Group
27
Aberdeen Group
United Kingdom
$4.39M +$1.63M +181,698 +48%
DTC
28
Deep Track Capital
Connecticut
$4.32M
Jacobs Levy Equity Management
29
Jacobs Levy Equity Management
New Jersey
$4.1M -$3.44M -382,818 -42%
PAM
30
Panagora Asset Management
Massachusetts
$3.84M +$1.78M +198,564 +68%
Hudson Bay Capital Management
31
Hudson Bay Capital Management
Connecticut
$3.81M +$216K +24,110 +5%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$3.76M +$444K +49,528 +12%
Two Sigma Investments
33
Two Sigma Investments
New York
$3.46M +$1.21M +134,712 +44%
EAM
34
Erste Asset Management
Austria
$3M
Squarepoint
35
Squarepoint
New York
$2.85M +$3.16M +351,979 +3,150%
Principal Financial Group
36
Principal Financial Group
Iowa
$2.77M +$36.9K +4,113 +1%
Millennium Management
37
Millennium Management
New York
$2.73M +$2.58M +287,551 +484%
CSS
38
Cubist Systematic Strategies
Connecticut
$2.64M +$1.61M +179,913 +116%
JP Morgan Chase
39
JP Morgan Chase
New York
$2.59M +$1.87M +208,182 +171%
Ameriprise
40
Ameriprise
Minnesota
$2.47M +$52.9K +5,895 +2%
ECM
41
ExodusPoint Capital Management
New York
$2.32M +$1.15M +128,109 +77%
Walleye Capital
42
Walleye Capital
New York
$1.95M +$2.23M +248,706 New
Public Sector Pension Investment Board (PSP Investments)
43
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$1.91M +$186K +20,681 +9%
Citadel Advisors
44
Citadel Advisors
Florida
$1.73M +$1.45M +161,784 +277%
Invesco
45
Invesco
Georgia
$1.7M -$3.94M -439,300 -67%
UBS AM
46
UBS AM
Illinois
$1.65M +$263K +29,275 +16%
Macquarie Group
47
Macquarie Group
Australia
$1.57M
Legal & General Group
48
Legal & General Group
United Kingdom
$1.42M -$24.4K -2,722 -1%
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$1.39M +$113K +12,547 +8%
TI
50
Trexquant Investment
Connecticut
$1.35M +$342K +38,060 +29%

XNCR Hedge Fund Activity: Q2 2025 in Review

193 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q2 2025, worth a combined $647M — down 23% from $838M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of XNCR and 24 opened new positions — a net loss of 8 holders — while 37 trimmed existing stakes and 93 added.

The largest buyer was Royal Bank of Canada, adding an estimated $11.7M. The largest seller was Loomis, Sayles & Company, exiting entirely with an estimated $11.4M sold.

  • 193 institutional investors held Xencor (XNCR) as of Q2 2025, down from 202 in Q1 2025.
  • Funds reported $647M of Xencor stock for Q2 2025, down 23% quarter-over-quarter.
  • 24 funds opened new Xencor positions in Q2 2025 and 32 closed out, a net change of -8 holders.
  • The largest Xencor buyer in Q2 2025 was Royal Bank of Canada, an estimated $11.7M added.
  • The largest Xencor seller in Q2 2025 was Loomis, Sayles & Company, an estimated $11.4M sold.

Based on aggregated 13F filings for Q2 2025.