Xencor
XNCR
203 hedge funds and large institutions have $1.02B invested in Xencor in 2026 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 70 increasing their positions, 65 reducing their positions, and 28 closing their positions.
5,900% more call options, than puts
Call options by funds: $60K | Put options by funds: $1K
8% more repeat investments, than reductions
Existing positions increased: 70 | Existing positions reduced: 65
0.52% more ownership
Funds ownership: 114.63% → 115.15% (+0.52%)
0% more funds holding in top 10
Funds holding in top 10: 3 → 3 (0)
7% less first-time investments, than exits
New positions opened: 26 | Existing positions closed: 28
2% less funds holding
Funds holding: 208 → 203 (-5)
19% less capital invested
Capital invested by funds: $1.25B → $1.02B (-$235M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$60.8M |
| 2 |
BlackRock
New York
|
+$13.8M |
| 3 |
Two Sigma Investments
New York
|
+$6.66M |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$5.51M |
| 5 |
VCIM
Velan Capital Investment Management
Alpharetta,
Georgia
|
+$3.1M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
DCM
Defilade Capital Management
Emeryville,
California
|
-$21.7M |
| 2 |
EC
EcoR1 Capital
San Francisco,
California
|
-$13.3M |
| 3 |
B
Braidwell
Stamford,
Connecticut
|
-$7.03M |
| 4 |
Bank of America
Charlotte,
North Carolina
|
-$3.27M |
| 5 |
Legal & General Group
London,
United Kingdom
|
-$2.99M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
226
Daiwa Securities Group
Tokyo,
Japan
| – | -$3K | -222 | Closed |
|
|
AAP
227
Arax Advisory Partners
Denver,
Colorado
| – | -$1.07K | -70 | Closed |
|
|
BWA
228
Basecamp Wealth Advisors
Bellevue,
Washington
| – | -$704 | -46 | Closed |
|
|
FHA
229
Flagship Harbor Advisors
Boston,
Massachusetts
| – | -$184 | -12 | Closed |
|
|
DF
230
Dunhill Financial
London,
United Kingdom
| – | -$8 | -1 | Closed |
|
XNCR Hedge Fund Activity: Q1 2026 in Review
203 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Xencor (XNCR) for Q1 2026, worth a combined $1.02B — down 19% from $1.25B a quarter earlier.
Sellers outnumbered buyers: 28 funds closed out of XNCR and 26 opened new positions — a net loss of 2 holders — while 65 trimmed existing stakes and 70 added.
The largest buyer was RA Capital Management, opening a new position worth an estimated $60.8M. The largest seller was Defilade Capital Management, exiting entirely with an estimated $21.7M sold.
- 203 institutional investors held Xencor (XNCR) as of Q1 2026, down from 208 in Q4 2025.
- Funds reported $1.02B of Xencor stock for Q1 2026, down 19% quarter-over-quarter.
- 26 funds opened new Xencor positions in Q1 2026 and 28 closed out, a net change of -2 holders.
- The largest Xencor buyer in Q1 2026 was RA Capital Management, an estimated $60.8M added.
- The largest Xencor seller in Q1 2026 was Defilade Capital Management, an estimated $21.7M sold.
Based on aggregated 13F filings for Q1 2026.