State Street Health Care Select Sector SPDR ETF
1,837 hedge funds and large institutions have $29.7B invested in State Street Health Care Select Sector SPDR ETF in 2025 Q4 according to their latest regulatory filings, with 317 funds opening new positions, 718 increasing their positions, 580 reducing their positions, and 93 closing their positions.
241% more first-time investments, than exits
New positions opened: 317 | Existing positions closed: 93
51% more funds holding in top 10
Funds holding in top 10: 61 → 92 (+31)
24% more repeat investments, than reductions
Existing positions increased: 718 | Existing positions reduced: 580
17% more capital invested
Capital invested by funds: $25.5B → $29.7B (+$4.24B)
11% more funds holding
Funds holding: 1,651 → 1,837 (+186)
0.64% more ownership
Funds ownership: 74.19% → 74.83% (+0.64%)
5% less call options, than puts
Call options by funds: $2.38B | Put options by funds: $2.5B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JP Morgan Chase
New York
|
+$443M |
| 2 |
RCMU
Rokos Capital Management (UK)
London,
United Kingdom
|
+$248M |
| 3 |
HIIFS
Harel Insurance Investments & Financial Services
Ramat Gan,
Israel
|
+$161M |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$146M |
| 5 |
Morgan Stanley
New York
|
+$133M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Caisse de Depot et Placement du Quebec (CDPQ)
Montreal,
Quebec, Canada
|
-$281M |
| 2 |
EMPI
Elo Mutual Pension Insurance
Espoo,
Finland
|
-$108M |
| 3 |
NSLI
Nan Shan Life Insurance
Taipei City,
Taiwan
|
-$96.4M |
| 4 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
-$94.6M |
| 5 |
Bank of America
Charlotte,
North Carolina
|
-$80.8M |
XLV Hedge Fund Activity: Q4 2025 in Review
1,837 of the 8,264 institutional investors tracked by Wall St. Rank reported a position in State Street Health Care Select Sector SPDR ETF (XLV) for Q4 2025, worth a combined $29.7B — up 17% from $25.5B a quarter earlier.
Buyers outnumbered sellers: 317 funds opened new XLV positions and 93 closed out — a net gain of 224 holders — while 718 added to existing stakes and 580 trimmed.
The largest buyer was JP Morgan Chase, adding an estimated $443M. The largest seller was Caisse de Depot et Placement du Quebec (CDPQ), cutting an estimated $281M.
- 1,837 institutional investors held State Street Health Care Select Sector SPDR ETF (XLV) as of Q4 2025, up from 1,651 in Q3 2025.
- Funds reported $29.7B of State Street Health Care Select Sector SPDR ETF stock for Q4 2025, up 17% quarter-over-quarter.
- 317 funds opened new State Street Health Care Select Sector SPDR ETF positions in Q4 2025 and 93 closed out, a net change of +224 holders.
- The largest State Street Health Care Select Sector SPDR ETF buyer in Q4 2025 was JP Morgan Chase, an estimated $443M added.
- The largest State Street Health Care Select Sector SPDR ETF seller in Q4 2025 was Caisse de Depot et Placement du Quebec (CDPQ), an estimated $281M sold.
Based on aggregated 13F filings for Q4 2025.