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80 hedge funds and large institutions have $65.8M invested in Exagen in 2025 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 33 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 8

106% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 16

29% more funds holding

Funds holding: 6280 (+18)

6.59% more ownership

Funds ownership: 41.14%47.72% (+6.6%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

34% less capital invested

Capital invested by funds: $99.5M → $65.8M (-$33.7M)

Holders
80
Holders Change
+18
Holders Change %
+29.03%
% of All Funds
0.97%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
26
Increased
33
Reduced
16
Closed
8
Calls
$432K
Puts
Net Calls
+$432K
Net Calls Change
-$162K
Name Holding Trade Value Shares
Change
Change in
Stake
Balyasny Asset Management
1
Balyasny Asset Management
Illinois
$5.59M +$1.78M +195,759 +27%
RI
2
RTW Investments
New York
$4.81M -$8.25M -906,404 -53%
Vanguard Group
3
Vanguard Group
Pennsylvania
$4.8M +$511K +56,187 +8%
SAM
4
Silvercrest Asset Management
New York
$3.64M +$714K +78,452 +15%
KCM
5
Kennedy Capital Management
Missouri
$2.92M -$654K -71,819 -13%
WC
6
Wexford Capital
Florida
$2.84M +$199K +21,851 +5%
Acadian Asset Management
7
Acadian Asset Management
Massachusetts
$2.52M +$2.74M +300,618 +264%
Two Sigma Investments
8
Two Sigma Investments
New York
$2.24M +$1.19M +130,271 +55%
MBAM
9
Mink Brook Asset Management
Florida
$2.15M +$2.86M +313,727 +784%
Susquehanna International Group
10
Susquehanna International Group
Pennsylvania
$1.84M +$921K +101,163 +50%
FCM
11
FourWorld Capital Management
New York
$1.66M +$419K +46,000 +20%
NCNMGF
12
Nano-Cap New Millennium Growth Fund
New York
$1.52M +$2.28M +250,000 New
Marshall Wace
13
Marshall Wace
United Kingdom
$1.48M +$1.99M +218,792 +888%
Millennium Management
14
Millennium Management
New York
$1.37M -$205K -22,564 -9%
Point72 Asset Management
15
Point72 Asset Management
Connecticut
$1.25M +$1.87M +205,200 New
Jane Street
16
Jane Street
New York
$1.18M +$835K +91,729 +90%
Ameriprise
17
Ameriprise
Minnesota
$1.17M +$583K +64,071 +50%
Citadel Advisors
18
Citadel Advisors
Florida
$1.15M +$657K +72,228 +62%
Russell Investments Group
19
Russell Investments Group
United Kingdom
$1.14M -$375K -41,193 -18%
MHP
20
Manatuck Hill Partners
Connecticut
$1.06M
Qube Research & Technologies (QRT)
21
Qube Research & Technologies (QRT)
United Kingdom
$1.06M +$888K +97,588 +127%
Geode Capital Management
22
Geode Capital Management
Massachusetts
$1.05M +$85.7K +9,417 +6%
MCM
23
Massar Capital Management
Connecticut
$1.03M
Two Sigma Advisers
24
Two Sigma Advisers
New York
$979K +$700K +76,900 +91%
Renaissance Technologies
25
Renaissance Technologies
New York
$839K +$1.26M +138,000 New

XGN Hedge Fund Activity: Q4 2025 in Review

80 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Exagen (XGN) for Q4 2025, worth a combined $65.8M — down 34% from $99.5M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new XGN positions and 8 closed out — a net gain of 18 holders — while 33 added to existing stakes and 16 trimmed.

The largest buyer was Mink Brook Asset Management, adding an estimated $2.86M. The largest seller was RTW Investments, cutting an estimated $8.25M.

  • 80 institutional investors held Exagen (XGN) as of Q4 2025, up from 62 in Q3 2025.
  • Funds reported $65.8M of Exagen stock for Q4 2025, down 34% quarter-over-quarter.
  • 26 funds opened new Exagen positions in Q4 2025 and 8 closed out, a net change of +18 holders.
  • The largest Exagen buyer in Q4 2025 was Mink Brook Asset Management, an estimated $2.86M added.
  • The largest Exagen seller in Q4 2025 was RTW Investments, an estimated $8.25M sold.

Based on aggregated 13F filings for Q4 2025.