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80 hedge funds and large institutions have $65.8M invested in Exagen in 2025 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 33 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 8

106% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 16

29% more funds holding

Funds holding: 6280 (+18)

6.59% more ownership

Funds ownership: 41.14%47.72% (+6.6%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

34% less capital invested

Capital invested by funds: $99.5M → $65.8M (-$33.7M)

Holders
80
Holders Change
+18
Holders Change %
+29.03%
% of All Funds
0.97%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
26
Increased
33
Reduced
16
Closed
8
Calls
$432K
Puts
Net Calls
+$432K
Net Calls Change
-$162K
Name Holding Trade Value Shares
Change
Change in
Stake
GCP
51
GSA Capital Partners
United Kingdom
$210K +$314K +34,546 New
SC
52
Shay Capital
New York
$205K +$307K +33,694 New
Man Group
53
Man Group
United Kingdom
$198K +$297K +32,606 New
D.E. Shaw & Co
54
D.E. Shaw & Co
New York
$192K +$287K +31,579 New
OQS
55
Occudo Quantitative Strategies
Florida
$184K +$85.1K +9,346 +45%
Corient Private Wealth
56
Corient Private Wealth
Florida
$177K +$265K +29,110 New
Dimensional Fund Advisors
57
Dimensional Fund Advisors
Texas
$160K -$9.37K -1,029 -4%
Hudson Bay Capital Management
58
Hudson Bay Capital Management
Connecticut
$147K +$220K +24,176 New
Barclays
59
Barclays
United Kingdom
$143K +$145K +15,965 +209%
DTL
60
Dynamic Technology Lab
Singapore
$129K +$194K +21,310 New
Walleye Capital
61
Walleye Capital
New York
$127K -$472K -51,876 -71%
Toronto Dominion Bank
62
Toronto Dominion Bank
Ontario, Canada
$122K
PCM
63
Perkins Capital Management
Minnesota
$113K -$13.7K -1,500 -7%
RS
64
R Squared
Hong Kong
$111K +$166K +18,192 New
Bank of America
65
Bank of America
North Carolina
$107K -$345K -37,952 -68%
JG
66
Jain Global
New York
$82.2K +$123K +13,514 New
PM
67
Penbrook Management
New York
$81.7K -$59K -6,480 -33%
SSA
68
Schonfeld Strategic Advisors
New York
$81.6K +$122K +13,421 New
PAP
69
Persistent Asset Partners
Hong Kong
$80.4K +$120K +13,230 New
BCM
70
BlueCrest Capital Management
Jersey
$60.8K +$91K +10,000 New
TC
71
Truvestments Capital
Florida
$37.5K +$29.4K +3,225 +110%
Canada Pension Plan Investment Board
72
Canada Pension Plan Investment Board
Ontario, Canada
$29.8K +$44.6K +4,900 New
Wells Fargo
73
Wells Fargo
California
$25.4K -$11K -1,210 -22%
JP Morgan Chase
74
JP Morgan Chase
New York
$23.7K -$110K -12,114 -76%
TRCT
75
Tower Research Capital (TRC)
New York
$21.4K +$32.1K +3,528 New

XGN Hedge Fund Activity: Q4 2025 in Review

80 of the 8,224 institutional investors tracked by Wall St. Rank reported a position in Exagen (XGN) for Q4 2025, worth a combined $65.8M — down 34% from $99.5M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new XGN positions and 8 closed out — a net gain of 18 holders — while 33 added to existing stakes and 16 trimmed.

The largest buyer was Mink Brook Asset Management, adding an estimated $2.86M. The largest seller was RTW Investments, cutting an estimated $8.25M.

  • 80 institutional investors held Exagen (XGN) as of Q4 2025, up from 62 in Q3 2025.
  • Funds reported $65.8M of Exagen stock for Q4 2025, down 34% quarter-over-quarter.
  • 26 funds opened new Exagen positions in Q4 2025 and 8 closed out, a net change of +18 holders.
  • The largest Exagen buyer in Q4 2025 was Mink Brook Asset Management, an estimated $2.86M added.
  • The largest Exagen seller in Q4 2025 was RTW Investments, an estimated $8.25M sold.

Based on aggregated 13F filings for Q4 2025.