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80 hedge funds and large institutions have $65.8M invested in Exagen in 2025 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 33 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

225% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 8

106% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 16

29% more funds holding

Funds holding: 6280 (+18)

6.59% more ownership

Funds ownership: 41.14%47.72% (+6.6%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

34% less capital invested

Capital invested by funds: $99.5M → $65.8M (-$33.7M)

Holders
80
Holders Change
+18
Holders Change %
+29.03%
% of All Funds
0.97%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
26
Increased
33
Reduced
16
Closed
8
Calls
$432K
Puts
Net Calls
+$432K
Net Calls Change
-$162K
Name Holding Trade Value Shares
Change
Change in
Stake
BNP Paribas Financial Markets
26
BNP Paribas Financial Markets
France
$810K +$786K +86,410 +185%
BlackRock
27
BlackRock
New York
$788K +$430K +47,246 +57%
SEI Investments
28
SEI Investments
Pennsylvania
$717K +$1.07M +118,005 New
UBS Group
29
UBS Group
Switzerland
$687K +$209K +22,978 +26%
6CM
30
683 Capital Management
New York
$654K +$979K +107,571 New
Morgan Stanley
31
Morgan Stanley
New York
$592K +$495K +54,361 +126%
XT
32
XTX Topco
Cayman Islands
$590K +$629K +69,161 +248%
JF
33
Jump Financial
Illinois
$583K +$872K +95,835 New
OAC
34
OMERS Administration Corp
Ontario, Canada
$547K +$819K +90,000 New
Squarepoint
35
Squarepoint
New York
$535K +$801K +88,032 New
Goldman Sachs
36
Goldman Sachs
New York
$496K +$180K +19,805 +32%
BCM
37
Bridgeway Capital Management
Texas
$469K +$450K +49,400 +178%
State Street
38
State Street
Massachusetts
$433K +$41.9K +4,600 +7%
HF
39
HRT Financial
New York
$423K +$635K +69,725 New
EGM
40
Engineers Gate Manager
New York
$383K +$198K +21,780 +53%
HA
41
Huntleigh Advisors
Missouri
$348K -$329K -36,165 -39%
TC
42
T3 Companies
New York
$347K +$519K +57,000 New
Calamos Advisors
43
Calamos Advisors
Illinois
$342K -$198K -21,784 -28%
TI
44
Trexquant Investment
Connecticut
$338K +$405K +44,504 +401%
CFG
45
Citizens Financial Group
Rhode Island
$332K -$26.4K -2,900 -5%
PWM
46
Palumbo Wealth Management
New York
$264K +$52K +5,718 +15%
ECM
47
ExodusPoint Capital Management
New York
$239K +$264K +29,037 +282%
SOW
48
State of Wyoming
Wyoming
$231K +$345K +37,943 New
Northern Trust
49
Northern Trust
Illinois
$228K +$60.3K +6,629 +21%
Bank of New York Mellon
50
Bank of New York Mellon
New York
$215K +$217K +23,870 +207%

XGN Hedge Fund Activity: Q4 2025 in Review

80 of the 8,224 institutional investors tracked by Wall St. Rank reported a position in Exagen (XGN) for Q4 2025, worth a combined $65.8M — down 34% from $99.5M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new XGN positions and 8 closed out — a net gain of 18 holders — while 33 added to existing stakes and 16 trimmed.

The largest buyer was Mink Brook Asset Management, adding an estimated $2.86M. The largest seller was RTW Investments, cutting an estimated $8.25M.

  • 80 institutional investors held Exagen (XGN) as of Q4 2025, up from 62 in Q3 2025.
  • Funds reported $65.8M of Exagen stock for Q4 2025, down 34% quarter-over-quarter.
  • 26 funds opened new Exagen positions in Q4 2025 and 8 closed out, a net change of +18 holders.
  • The largest Exagen buyer in Q4 2025 was Mink Brook Asset Management, an estimated $2.86M added.
  • The largest Exagen seller in Q4 2025 was RTW Investments, an estimated $8.25M sold.

Based on aggregated 13F filings for Q4 2025.