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XBiotech

41 hedge funds and large institutions have $5.48M invested in XBiotech in 2025 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 8 increasing their positions, 17 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,400% more call options, than puts

Call options by funds: $45K | Put options by funds: $3K

2.1% less ownership

Funds ownership: 9.63%7.53% (-2.1%)

15% less funds holding

Funds holding: 4841 (-7)

30% less capital invested

Capital invested by funds: $7.81M → $5.48M (-$2.32M)

50% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 8

53% less repeat investments, than reductions

Existing positions increased: 8 | Existing positions reduced: 17

Holders
41
Holders Change
-7
Holders Change %
-14.58%
% of All Funds
0.5%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
4
Increased
8
Reduced
17
Closed
8
Calls
$45K
Puts
$3K
Net Calls
+$42K
Net Calls Change
+$45K
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$716K -$1.28M -519,683 -63%
BlackRock
2
BlackRock
New York
$690K -$33.9K -13,754 -5%
Geode Capital Management
3
Geode Capital Management
Massachusetts
$529K -$1.83K -742 -0.3%
RC
4
RBF Capital
California
$474K -$3.69K -1,499 -0.7%
Ameriprise
5
Ameriprise
Minnesota
$446K +$461K +186,796 New
Morgan Stanley
6
Morgan Stanley
New York
$391K +$103K +41,966 +35%
Millennium Management
7
Millennium Management
New York
$324K -$693K -280,906 -67%
BCM
8
Bridgeway Capital Management
Texas
$214K +$74K +30,000 +50%
Northern Trust
9
Northern Trust
Illinois
$183K -$12.8K -5,185 -6%
State Street
10
State Street
Massachusetts
$174K +$14.1K +5,700 +8%
Jane Street
11
Jane Street
New York
$167K +$34.4K +13,971 +25%
Squarepoint
12
Squarepoint
New York
$153K +$4.55K +1,845 +3%
EF
13
Empowered Funds
Pennsylvania
$142K
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$121K -$33.6K -13,621 -21%
Bank of New York Mellon
15
Bank of New York Mellon
New York
$116K
Bank of America
16
Bank of America
North Carolina
$85.8K -$28.3K -11,494 -24%
Connor, Clark & Lunn Investment Management (CC&L)
17
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$72.2K -$14.3K -5,800 -16%
BNP Paribas Financial Markets
18
BNP Paribas Financial Markets
France
$64.2K +$15.4K +6,254 +30%
National Bank of Canada
19
National Bank of Canada
Quebec, Canada
$58.8K
XT
20
XTX Topco
Cayman Islands
$51.9K +$16.4K +6,647 +44%
Qube Research & Technologies (QRT)
21
Qube Research & Technologies (QRT)
United Kingdom
$49.3K -$23.9K -9,706 -32%
American Century Companies
22
American Century Companies
Missouri
$45.1K
Goldman Sachs
23
Goldman Sachs
New York
$40.2K -$20.1K -8,171 -33%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$39K
PAP
25
Persistent Asset Partners
Hong Kong
$32.4K +$33.4K +13,565 New

XBIT Hedge Fund Activity: Q4 2025 in Review

41 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in XBiotech (XBIT) for Q4 2025, worth a combined $5.48M — down 30% from $7.81M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of XBIT and 4 opened new positions — a net loss of 4 holders — while 17 trimmed existing stakes and 8 added.

The largest buyer was Ameriprise, opening a new position worth an estimated $461K. The largest seller was Vanguard Group, cutting an estimated $1.28M.

  • 41 institutional investors held XBiotech (XBIT) as of Q4 2025, down from 48 in Q3 2025.
  • Funds reported $5.48M of XBiotech stock for Q4 2025, down 30% quarter-over-quarter.
  • 4 funds opened new XBiotech positions in Q4 2025 and 8 closed out, a net change of -4 holders.
  • The largest XBiotech buyer in Q4 2025 was Ameriprise, an estimated $461K added.
  • The largest XBiotech seller in Q4 2025 was Vanguard Group, an estimated $1.28M sold.

Based on aggregated 13F filings for Q4 2025.