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State Street SPDR S&P Biotech ETF
XBI

Name Holding Trade Value Shares
Change 		Change in
Stake
Two Sigma Investments
776
Two Sigma Investments
New York
– -$29.8M -321,400 Closed
BU
777
Brown University
Rhode Island
– -$24.8M -268,000 Closed
CHP
778
Castle Hook Partners
New York
– -$19.8M -213,424 Closed
EP
779
Eversept Partners
New York
– -$9.27M -100,000 Closed
SFC
780
Strategic Financial Concepts
Texas
– -$14.9K -94,191 Closed
BFIC
781
Bedell Frazier Investment Counselling
California
– -$6.12M -66,009 Closed
CRM
782
Cramer Rosenthal McGlynn
Connecticut
– -$5.25M -56,624 Closed
CCMG
783
Clark Capital Management Group
Pennsylvania
– -$4.31M -46,488 Closed
LF
784
Longbow Finance
Switzerland
– -$4.1M -44,256 Closed
AAA
785
Affinity Asset Advisors
New York
– -$3.48M -37,550 Closed
BKA
786
Brick & Kyle Associates
Pennsylvania
– -$3.02M -32,631 Closed
Capstone Investment Advisors
787
Capstone Investment Advisors
New York
– -$2.94M -29,898 Closed
EE
788
EWG Elevate
California
– -$2.16M -23,289 Closed
PA
789
Perceptive Advisors
New York
– -$2.23M -22,665 Closed
LHWM
790
Lake Hills Wealth Management
Texas
– -$2.07M -22,360 Closed
IMC Chicago
791
IMC Chicago
Illinois
– -$1.59M -17,194 Closed
BCM
792
Bayesian Capital Management
New York
– -$1.59M -17,100 Closed
QIM
793
Quantitative Investment Management
Virginia
– -$1.45M -15,683 Closed
CAS
794
CTC Alternative Strategies
Illinois
– -$1.21M -13,000 Closed
CSS
795
Cubist Systematic Strategies
Connecticut
– -$1.19M -12,100 Closed
EL
796
Essex LLC
Illinois
– -$967K -10,430 Closed
YIH
797
Y-Intercept (HK)
Hong Kong
– -$842K -9,083 Closed
HHGC
798
Hunting Hill Global Capital
New York
– -$716K -7,723 Closed
AGM
799
Alpine Global Management
New York
– -$612K -6,599 Closed
GCM
800
Greenland Capital Management
New York
– -$590K -6,365 Closed
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32
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