|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$59.3M
|
–
|
–
|
–
|
|
|
2
|
Adage Capital Partners
Boston,
Massachusetts
|
$38.9M
|
+$9.88M
|
+717,996
|
+50%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$37.3M
|
-$4.33M
|
-314,608
|
-13%
|
|
|
4
|
Millennium Management
New York
|
$15.8M
|
+$1.58M
|
+114,981
|
+15%
|
|
|
5
|
AWM Investment Company
New York
|
$14.4M
|
–
|
–
|
–
|
|
|
6
|
Cormorant Asset Management
Boston,
Massachusetts
|
$11.3M
|
+$8.58M
|
+623,409
|
New
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
$11.1M
|
+$3.72M
|
+270,351
|
+79%
|
|
|
8
|
|
$8.82M
|
+$1.73M
|
+125,900
|
+35%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.62M
|
+$566K
|
+41,144
|
+11%
|
|
|
10
|
RA Capital Management
Boston,
Massachusetts
|
$5.81M
|
–
|
–
|
–
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$5.58M
|
+$97.2K
|
+7,061
|
+2%
|
|
|
12
|
Ghost Tree Capital
New York
|
$4.98M
|
+$344K
|
+25,000
|
+10%
|
|
|
13
|
Boxer Capital
San Diego,
California
|
$4.53M
|
+$3.44M
|
+250,270
|
New
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$4.4M
|
+$3.34M
|
+242,905
|
New
|
|
|
15
|
|
$3.69M
|
-$2.69M
|
-195,164
|
-49%
|
|
|
16
|
|
$3.68M
|
+$1.14M
|
+82,539
|
+68%
|
|
|
17
|
Perceptive Advisors
New York
|
$3.62M
|
–
|
–
|
–
|
|
|
18
|
DAFNA Capital Management
Los Angeles,
California
|
$3.5M
|
+$1.68M
|
+122,339
|
+173%
|
|
|
19
|
Baker Bros. Advisors
New York
|
$3.4M
|
–
|
–
|
–
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$2.73M
|
+$401K
|
+29,159
|
+24%
|
|
|
21
|
Putnam Investments
Boston,
Massachusetts
|
$2.53M
|
–
|
–
|
–
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$2.47M
|
+$59.7K
|
+4,337
|
+3%
|
|
|
23
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.41M
|
+$1.83M
|
+133,000
|
New
|
|
|
24
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.17M
|
+$1.65M
|
+120,000
|
New
|
|
|
25
|
Balyasny Asset Management
Chicago,
Illinois
|
$2.1M
|
+$1.59M
|
+115,800
|
New
|
|
