|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$165M
|
+$34.7M
|
+1,789,593
|
+23%
|
|
|
2
|
Paradigm Biocapital Advisors
New York
|
$88.1M
|
+$4.59M
|
+236,932
|
+5%
|
|
|
3
|
State Street
Boston,
Massachusetts
|
$78.6M
|
+$34.5M
|
+1,780,232
|
+66%
|
|
|
4
|
|
$68M
|
+$931
|
+48
|
+0%
|
|
|
5
|
|
$66.8M
|
+$7.49M
|
+386,180
|
+11%
|
|
|
6
|
Perceptive Advisors
New York
|
$64M
|
+$37.4M
|
+1,926,887
|
+111%
|
|
|
7
|
Deep Track Capital
Greenwich,
Connecticut
|
$60.5M
|
-$3.41M
|
-175,675
|
-5%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$56.6M
|
+$4.52M
|
+233,331
|
+8%
|
|
|
9
|
Maverick Capital
Dallas,
Texas
|
$47.1M
|
+$7.11M
|
+366,573
|
+16%
|
|
|
10
|
Commodore Capital
New York
|
$33.9M
|
+$205K
|
+10,579
|
+0.5%
|
|
|
11
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$32.3M
|
+$9.23M
|
+476,190
|
+35%
|
|
|
12
|
AllianceBernstein
Nashville,
Tennessee
|
$30.2M
|
-$6.53M
|
-336,645
|
-16%
|
|
|
13
|
Vivo Capital
Palo Alto,
California
|
$29.4M
|
–
|
–
|
–
|
|
|
14
|
Great Point Partners
Greenwich,
Connecticut
|
$23.4M
|
+$25.9M
|
+1,335,000
|
New
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$23.3M
|
+$21.3M
|
+1,098,574
|
+470%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$20.4M
|
+$3.29M
|
+169,804
|
+17%
|
|
|
17
|
Novo Holdings A/S
Hellerup,
Denmark
|
$19.3M
|
+$21.3M
|
+1,100,000
|
New
|
|
|
18
|
Pictet Asset Management
Carouge,
Switzerland
|
$19.2M
|
+$864K
|
+44,565
|
+4%
|
|
|
19
|
Yiheng Capital Management
San Francisco,
California
|
$16.6M
|
-$5.44M
|
-280,404
|
-23%
|
|
|
20
|
Polar Capital Holdings
London,
United Kingdom
|
$15.6M
|
-$1.76M
|
-90,719
|
-9%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$13.3M
|
-$2.41M
|
-124,230
|
-14%
|
|
|
22
|
5AM Venture Management
San Francisco,
California
|
$12.9M
|
+$2.91M
|
+150,000
|
+26%
|
|
|
23
|
Logos Global Management
San Francisco,
California
|
$12.3M
|
+$1.94M
|
+100,000
|
+17%
|
|
|
24
|
Tang Capital Management
San Diego,
California
|
$12.1M
|
–
|
–
|
–
|
|
|
25
|
Ghost Tree Capital
New York
|
$10.9M
|
+$6.3M
|
+325,000
|
+108%
|
|
