|
1
|
RA Capital Management
Boston,
Massachusetts
|
$479M
|
+$470M
|
+556,049
|
New
|
|
|
2
|
5AM Venture Management
San Francisco,
California
|
$288M
|
+$283M
|
+334,621
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$147M
|
+$156M
|
+183,852
|
New
|
|
|
4
|
Woodline Partners
San Francisco,
California
|
$49.7M
|
+$48.8M
|
+57,663
|
New
|
|
|
5
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$46.3M
|
+$45.5M
|
+53,733
|
New
|
|
|
6
|
|
$35.9M
|
+$35.3M
|
+41,667
|
New
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$34.8M
|
+$34.1M
|
+40,328
|
New
|
|
|
8
|
|
$33.1M
|
+$32.5M
|
+38,391
|
New
|
|
|
9
|
Sarissa Capital Management
Greenwich,
Connecticut
|
$30.5M
|
+$29.9M
|
+35,351
|
New
|
|
|
10
|
Laurion Capital Management
New York
|
$25.2M
|
+$24.8M
|
+29,283
|
New
|
|
|
11
|
|
$23.7M
|
+$23.3M
|
+27,500
|
New
|
|
|
12
|
Putnam Investments
Boston,
Massachusetts
|
$23.7M
|
+$23.3M
|
+27,500
|
New
|
|
|
13
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$23.1M
|
+$22.6M
|
+26,763
|
New
|
|
|
14
|
Gilder Gagnon Howe & Co
New York
|
$14.3M
|
+$14M
|
+16,576
|
New
|
|
|
15
|
Thrivent Financial for Lutherans
Minneapolis,
Minnesota
|
$12M
|
+$11.8M
|
+13,889
|
New
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$8.11M
|
+$7.96M
|
+9,411
|
New
|
|
|
17
|
Trustees of Columbia University in the City of New York
New York
|
$7.92M
|
+$7.78M
|
+9,191
|
New
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$7.31M
|
+$7.17M
|
+8,477
|
New
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$5.26M
|
+$5.16M
|
+6,098
|
New
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$3.16M
|
+$3.1M
|
+3,662
|
New
|
|
|
21
|
Bollard Group
Boston,
Massachusetts
|
$2.39M
|
+$2.35M
|
+2,778
|
New
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$1.79M
|
+$1.76M
|
+2,076
|
New
|
|
|
23
|
|
$1.39M
|
+$1.37M
|
+1,614
|
New
|
|
|
24
|
Bank of New York Mellon
New York
|
$1.3M
|
+$1.28M
|
+1,507
|
New
|
|
|
25
|
Zweig-DiMenna Associates
New York
|
$862K
|
+$846K
|
+1,000
|
New
|
|
