|
1
|
Janus Henderson Investors US
Denver,
Colorado
|
$3.36M
|
-$160K
|
-27,241
|
-5%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$2.54M
|
–
|
–
|
–
|
|
|
3
|
Franklin Resources
San Mateo,
California
|
$2.44M
|
–
|
–
|
–
|
|
|
4
|
Avoro Capital Advisors
New York
|
$1.4M
|
–
|
–
|
–
|
|
|
5
|
International Biotechnology Trust
London,
United Kingdom
|
$1.36M
|
–
|
–
|
–
|
|
|
6
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$789K
|
+$166K
|
+28,272
|
+28%
|
|
|
7
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$677K
|
–
|
–
|
–
|
|
|
8
|
New Leaf Venture Partners
New York
|
$641K
|
+$43.4K
|
+7,400
|
+8%
|
|
|
9
|
Victory Capital Management
San Antonio,
Texas
|
$479K
|
+$130K
|
+22,171
|
+40%
|
|
|
10
|
Creative Planning
Overland Park,
Kansas
|
$161K
|
–
|
–
|
–
|
|
|
11
|
Prelude Capital Management
New York
|
$145K
|
–
|
–
|
–
|
|
|
12
|
|
$143K
|
+$136K
|
+23,225
|
New
|
|
|
13
|
Wells Fargo
San Francisco,
California
|
$109K
|
+$26.4K
|
+4,500
|
+34%
|
|
|
14
|
Millennium Management
New York
|
$62K
|
-$24.5K
|
-4,174
|
-29%
|
|
|
15
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$45K
|
+$7.62K
|
+1,300
|
+21%
|
|
|
16
|
Federation des caisses Desjardins du Quebec
Levis,
Quebec, Canada
|
$16.1K
|
+$15.6K
|
+2,666
|
New
|
|
|
17
|
1832 Asset Management
Toronto,
Ontario, Canada
|
$15K
|
+$14.7K
|
+2,500
|
New
|
|
|
18
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$13K
|
+$8.83K
|
+1,507
|
+261%
|
|
|
19
|
UBS Group
Zurich,
Switzerland
|
$12K
|
+$4.22K
|
+720
|
+56%
|
|
|
20
|
Bank of America
Charlotte,
North Carolina
|
$7K
|
-$86.2K
|
-14,700
|
-93%
|
|
|
21
|
|
$4K
|
+$4.1K
|
+700
|
New
|
|
|
22
|
Tower Research Capital (TRC)
New York
|
$1K
|
-$1.17K
|
-200
|
-67%
|
|
|
23
|
Opaleye Management
Boston,
Massachusetts
|
–
|
-$622K
|
-110,000
|
Closed
|
|
|
24
|
Putnam Investments
Boston,
Massachusetts
|
–
|
-$470K
|
-83,111
|
Closed
|
|
|
25
|
Credit Suisse
Zurich,
Switzerland
|
–
|
-$143K
|
-25,382
|
Closed
|
|
