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Tango Therapeutics

115 hedge funds and large institutions have $652M invested in Tango Therapeutics in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 30 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,265% more call options, than puts

Call options by funds: $1.32M | Put options by funds: $97K

342% more capital invested

Capital invested by funds: $147M → $652M (+$504M)

75% more funds holding in top 10

Funds holding in top 10: 47 (+3)

40% more repeat investments, than reductions

Existing positions increased: 42 | Existing positions reduced: 30

18.15% more ownership

Funds ownership: 99.24%117.39% (+18%)

6% less funds holding

Funds holding: 122115 (-7)

25% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 28

Holders
115
Holders Change
-7
Holders Change %
-5.74%
% of All Funds
1.51%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.09%
New
21
Increased
42
Reduced
30
Closed
28
Calls
$1.32M
Puts
$97K
Net Calls
+$1.23M
Net Calls Change
+$1.23M
Name Holding Trade Value Shares
Change
Change in
Stake
Goldman Sachs
51
Goldman Sachs
New York
$554K -$159K -64,254 -37%
AllianceBernstein
52
AllianceBernstein
Tennessee
$543K +$102K +41,070 +63%
DekaBank Deutsche Girozentrale
53
DekaBank Deutsche Girozentrale
Germany
$502K
Invesco
54
Invesco
Georgia
$488K +$61.3K +24,776 +35%
Acadian Asset Management
55
Acadian Asset Management
Massachusetts
$419K -$2.2M -891,356 -92%
AQR Capital Management
56
AQR Capital Management
Connecticut
$404K -$156K -63,162 -44%
JP Morgan Chase
57
JP Morgan Chase
New York
$341K +$87.6K +35,439 +113%
Renaissance Technologies
58
Renaissance Technologies
New York
$335K -$270K -109,000 -62%
PAMP
59
Polar Asset Management Partners
Ontario, Canada
$287K +$139K +56,100 New
XT
60
XTX Topco
Cayman Islands
$286K -$278K -112,339 -67%
Citadel Advisors
61
Citadel Advisors
Florida
$282K -$127K -51,437 -48%
Deutsche Bank
62
Deutsche Bank
Germany
$270K -$2.79K -1,127 -2%
Simplex Trading
63
Simplex Trading
Illinois
$255K +$123K +49,901 New
Wells Fargo
64
Wells Fargo
California
$252K +$65.3K +26,422 +116%
MIM
65
MetLife Investment Management
New Jersey
$244K +$118K +47,726 New
Bank of America
66
Bank of America
North Carolina
$241K -$753K -304,344 -87%
IIM
67
INTECH Investment Management
Florida
$234K +$13.6K +5,518 +14%
Mirae Asset Global ETFs Holdings
68
Mirae Asset Global ETFs Holdings
Hong Kong
$215K +$33K +13,360 +47%
AI
69
Allostery Investments
Connecticut
$205K +$98.9K +40,000 New
Janney Montgomery Scott
70
Janney Montgomery Scott
Pennsylvania
$202K
T. Rowe Price Associates
71
T. Rowe Price Associates
Maryland
$197K +$39.9K +16,149 +73%
CHAM
72
Clear Harbor Asset Management
Connecticut
$155K
Citigroup
73
Citigroup
New York
$155K -$28.5K -11,532 -28%
Manulife (Manufacturers Life Insurance)
74
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$147K +$23.2K +9,367 +48%
SW
75
Simplicity Wealth
New Jersey
$138K

TNGX Hedge Fund Activity: Q2 2025 in Review

115 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Tango Therapeutics (TNGX) for Q2 2025, worth a combined $652M — up 342% from $147M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of TNGX and 21 opened new positions — a net loss of 7 holders — while 30 trimmed existing stakes and 42 added.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $14.6M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $3.23M.

  • 115 institutional investors held Tango Therapeutics (TNGX) as of Q2 2025, down from 122 in Q1 2025.
  • Funds reported $652M of Tango Therapeutics stock for Q2 2025, up 342% quarter-over-quarter.
  • 21 funds opened new Tango Therapeutics positions in Q2 2025 and 28 closed out, a net change of -7 holders.
  • The largest Tango Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $14.6M added.
  • The largest Tango Therapeutics seller in Q2 2025 was Blue Owl Capital Holdings, an estimated $3.23M sold.

Based on aggregated 13F filings for Q2 2025.