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Tango Therapeutics

115 hedge funds and large institutions have $652M invested in Tango Therapeutics in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 42 increasing their positions, 30 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,265% more call options, than puts

Call options by funds: $1.32M | Put options by funds: $97K

342% more capital invested

Capital invested by funds: $147M → $652M (+$504M)

75% more funds holding in top 10

Funds holding in top 10: 47 (+3)

40% more repeat investments, than reductions

Existing positions increased: 42 | Existing positions reduced: 30

18.15% more ownership

Funds ownership: 99.24%117.39% (+18%)

6% less funds holding

Funds holding: 122115 (-7)

25% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 28

Holders
115
Holders Change
-7
Holders Change %
-5.74%
% of All Funds
1.51%
Holding in Top 10
7
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+75%
% of All Funds
0.09%
New
21
Increased
42
Reduced
30
Closed
28
Calls
$1.32M
Puts
$97K
Net Calls
+$1.23M
Net Calls Change
+$1.23M
Name Holding Trade Value Shares
Change
Change in
Stake
Bessemer Group
26
Bessemer Group
New Jersey
$3.63M
ACH
27
ArrowMark Colorado Holdings
Colorado
$3.63M
Charles Schwab
28
Charles Schwab
California
$3.08M +$132K +53,433 +10%
Northern Trust
29
Northern Trust
Illinois
$3.07M +$374K +151,126 +34%
VC
30
Vivo Capital
California
$3.07M +$1.48M +600,000 New
Morgan Stanley
31
Morgan Stanley
New York
$2.74M +$702K +284,102 +113%
Dimensional Fund Advisors
32
Dimensional Fund Advisors
Texas
$2.69M -$198K -80,192 -13%
N
33
Nuveen
North Carolina
$2.27M +$595K +240,780 +119%
RAM
34
Readystate Asset Management
Illinois
$2.14M +$1.03M +418,517 New
UBS Group
35
UBS Group
Switzerland
$1.42M +$306K +123,767 +81%
Royal Bank of Canada
36
Royal Bank of Canada
Ontario, Canada
$1.29M +$620K +250,852 +17,653%
Susquehanna International Group
37
Susquehanna International Group
Pennsylvania
$1.24M +$435K +175,832 +264%
CAM
38
Congress Asset Management
Massachusetts
$1.16M -$413 -167 -0.1%
Fisher Asset Management
39
Fisher Asset Management
Washington
$1.15M
Jacobs Levy Equity Management
40
Jacobs Levy Equity Management
New Jersey
$1.12M -$1.28M -519,176 -70%
SB
41
Samsara BioCapital
California
$1.08M -$1.04M -420,000 -67%
SC
42
Stempoint Capital
New York
$1.07M +$516K +208,800 New
TGV
43
TRV GP VI
Massachusetts
$994K
FAM
44
Fred Alger Management
New York
$980K +$473K +191,337 New
Bank of New York Mellon
45
Bank of New York Mellon
New York
$963K +$185K +74,764 +66%
SFI
46
Susquehanna Fundamental Investments
Pennsylvania
$818K -$180K -72,929 -31%
Barclays
47
Barclays
United Kingdom
$710K +$187K +75,618 +120%
Franklin Resources
48
Franklin Resources
California
$641K +$846 +342 +0.3%
BCM
49
Bridgeway Capital Management
Texas
$640K
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$575K +$112K +45,467 +68%

TNGX Hedge Fund Activity: Q2 2025 in Review

115 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Tango Therapeutics (TNGX) for Q2 2025, worth a combined $652M — up 342% from $147M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of TNGX and 21 opened new positions — a net loss of 7 holders — while 30 trimmed existing stakes and 42 added.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $14.6M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $3.23M.

  • 115 institutional investors held Tango Therapeutics (TNGX) as of Q2 2025, down from 122 in Q1 2025.
  • Funds reported $652M of Tango Therapeutics stock for Q2 2025, up 342% quarter-over-quarter.
  • 21 funds opened new Tango Therapeutics positions in Q2 2025 and 28 closed out, a net change of -7 holders.
  • The largest Tango Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $14.6M added.
  • The largest Tango Therapeutics seller in Q2 2025 was Blue Owl Capital Holdings, an estimated $3.23M sold.

Based on aggregated 13F filings for Q2 2025.