Thermo Fisher Scientific
TMO
2,701 hedge funds and large institutions have $231B invested in Thermo Fisher Scientific in 2025 Q4 according to their latest regulatory filings, with 369 funds opening new positions, 945 increasing their positions, 1,038 reducing their positions, and 120 closing their positions.
208% more first-time investments, than exits
New positions opened: 369 | Existing positions closed: 120
53% more funds holding in top 10
Funds holding in top 10: 74 → 113 (+39)
44% more capital invested
Capital invested by funds: $161B → $231B (+$70.2B)
12.14% more ownership
Funds ownership: 87.83% → 99.98% (+12%)
8% more funds holding
Funds holding: 2,511 → 2,701 (+190)
9% less repeat investments, than reductions
Existing positions increased: 945 | Existing positions reduced: 1,038
37% less call options, than puts
Call options by funds: $1.36B | Put options by funds: $2.18B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JSC
J. Stern & Co
London,
United Kingdom
|
+$17.8B |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$1.24B |
| 3 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
+$743M |
| 4 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$719M |
| 5 |
T. Rowe Price Associates
Baltimore,
Maryland
|
+$696M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Morgan Stanley
New York
|
-$468M |
| 2 |
Kovitz Investment Group Partners
Chicago,
Illinois
|
-$399M |
| 3 |
JP Morgan Chase
New York
|
-$374M |
| 4 |
FCM
Farallon Capital Management
San Francisco,
California
|
-$352M |
| 5 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
-$342M |
TMO Hedge Fund Activity: Q4 2025 in Review
2,701 institutional investors reported a position in Thermo Fisher Scientific (TMO) for Q4 2025, worth a combined $231B — up 44% from $161B a quarter earlier.
Buyers outnumbered sellers: 369 funds opened new TMO positions and 120 closed out — a net gain of 249 holders — while 945 added to existing stakes and 1,038 trimmed.
The largest buyer was J. Stern & Co, adding an estimated $17.8B. The largest seller was Morgan Stanley, cutting an estimated $468M.
- 2,701 institutional investors held Thermo Fisher Scientific (TMO) as of Q4 2025, up from 2,511 in Q3 2025.
- Funds reported $231B of Thermo Fisher Scientific stock for Q4 2025, up 44% quarter-over-quarter.
- 369 funds opened new Thermo Fisher Scientific positions in Q4 2025 and 120 closed out, a net change of +249 holders.
- The largest Thermo Fisher Scientific buyer in Q4 2025 was J. Stern & Co, an estimated $17.8B added.
- The largest Thermo Fisher Scientific seller in Q4 2025 was Morgan Stanley, an estimated $468M sold.
Based on aggregated 13F filings for Q4 2025.