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Talphera
TLPH

Name Holding Trade Value Shares
Change 		Change in
Stake
PA
1
Perceptive Advisors
New York
$46.4M +$35.7M +250,420 New
Fidelity Investments
2
Fidelity Investments
Massachusetts
$8.23M +$6.33M +44,402 New
SC
3
Sophrosyne Capital
New York
$6.79M +$5.23M +36,645 New
BFA
4
BlackRock Fund Advisors
California
$4.83M +$3.71M +26,044 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$4.75M +$3.65M +25,594 New
AP
6
Alydar Partners
Massachusetts
$4.56M +$3.51M +24,616 New
EI
7
EAM Investors
California
$4.36M +$3.35M +23,522 New
RFC
8
Russell Frank Company
Washington
$2.01M +$1.55M +10,860 New
State Street
9
State Street
Massachusetts
$1.99M +$1.53M +10,710 New
BIT
10
BlackRock Institutional Trust
California
$1.97M +$1.51M +10,616 New
DCM
11
Driehaus Capital Management
Illinois
$1.75M +$1.34M +9,417 New
SKK
12
Shepherd Kaplan Krochuk
Massachusetts
$1.75M +$1.34M +9,417 New
AC
13
Ascend Capital
California
$1.58M +$1.21M +8,513 New
Allianz Asset Management
14
Allianz Asset Management
Germany
$1.5M +$1.15M +8,085 New
Bank of New York Mellon
15
Bank of New York Mellon
New York
$1.41M +$1.08M +7,585 New
Ameriprise
16
Ameriprise
Minnesota
$1.22M +$937K +6,570 New
ICAP
17
Independence Capital Asset Partners
Colorado
$1.15M +$885K +6,205 New
BCM
18
Bridgeway Capital Management
Texas
$1.05M +$804K +5,640 New
TCIM
19
TIAA CREF Investment Management
New York
$1.03M +$792K +5,556 New
Deutsche Bank
20
Deutsche Bank
Germany
$980K +$755K +5,293 New
SIM
21
Spark Investment Management
New York
$962K +$740K +5,185 New
Northern Trust
22
Northern Trust
Illinois
$915K +$704K +4,939 New
Geode Capital Management
23
Geode Capital Management
Massachusetts
$713K +$548K +3,845 New
MWP
24
MYCIO Wealth Partners
Pennsylvania
$695K +$535K +3,750 New
FSA
25
Franklin Street Advisors
North Carolina
$661K +$508K +3,565 New
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