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THRD

Third Harmonic Bio

Delisted

THRD was delisted on the 30th of July, 2025.

50 hedge funds and large institutions have $153M invested in Third Harmonic Bio in 2022 Q4 according to their latest regulatory filings, with 28 funds opening new positions, 6 increasing their positions, 10 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

56% more first-time investments, than exits

New positions opened: 28 | Existing positions closed: 18

25% more funds holding

Funds holding: 4050 (+10)

3.84% less ownership

Funds ownership: 91.67%87.83% (-3.8%)

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

40% less repeat investments, than reductions

Existing positions increased: 6 | Existing positions reduced: 10

73% less capital invested

Capital invested by funds: $563M → $153M (-$410M)

Holders
50
Holders Change
+10
Holders Change %
+25%
% of All Funds
0.8%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
28
Increased
6
Reduced
10
Closed
18
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
AVLSA
1
Atlas Venture Life Science Advisors
Massachusetts
$46.9M
O
2
OrbiMed
New York
$24.9M
BI
3
BVF Inc
California
$18.8M +$14.5M +864,119 +25%
GA
4
General Atlantic
New York
$12.7M
SCM
5
Stonepine Capital Management
Oregon
$8.67M +$33.7M +2,015,301 New
TCM
6
Tang Capital Management
California
$7.31M +$28.4M +1,700,000 New
BCLSI
7
Bain Capital Life Sciences Investors
Massachusetts
$4.95M -$18.9M -1,128,425 -49%
CC
8
Commodore Capital
New York
$4.27M -$423K -25,275 -2%
BlackRock
9
BlackRock
New York
$3.22M +$12.5M +748,748 New
Vanguard Group
10
Vanguard Group
Pennsylvania
$2.99M +$9.98M +596,370 +596%
RI
11
RTW Investments
New York
$2.62M
BC
12
Boxer Capital
California
$2.45M
RCM
13
RA Capital Management
Massachusetts
$2.3M -$49.2M -2,941,000 -85%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$1.97M -$223K -13,299 -3%
DTC
15
Deep Track Capital
Connecticut
$1.92M -$13.8M -822,648 -65%
Wellington Management Group
16
Wellington Management Group
Massachusetts
$1.46M -$13.9M -828,094 -71%
Millennium Management
17
Millennium Management
New York
$1.17M +$1.56M +92,954 +52%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$991K +$3.86M +230,610 New
State Street
19
State Street
Massachusetts
$836K +$3.25M +194,430 New
Northern Trust
20
Northern Trust
Illinois
$443K +$1.72M +102,933 New
HS
21
HighVista Strategies
Massachusetts
$395K +$1.54M +91,780 New
Charles Schwab
22
Charles Schwab
California
$376K +$1.47M +87,555 New
Walleye Capital
23
Walleye Capital
New York
$245K +$952K +56,900 New
Morgan Stanley
24
Morgan Stanley
New York
$200K +$659K +39,375 +550%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$160K +$621K +37,094 New

THRD Hedge Fund Activity: Q4 2022 in Review

50 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Third Harmonic Bio (THRD) for Q4 2022, worth a combined $153M — down 73% from $563M a quarter earlier.

Buyers outnumbered sellers: 28 funds opened new THRD positions and 18 closed out — a net gain of 10 holders — while 6 added to existing stakes and 10 trimmed.

The largest buyer was Stonepine Capital Management, opening a new position worth an estimated $33.7M. The largest seller was RA Capital Management, cutting an estimated $49.2M.

  • 50 institutional investors held Third Harmonic Bio (THRD) as of Q4 2022, up from 40 in Q3 2022.
  • Funds reported $153M of Third Harmonic Bio stock for Q4 2022, down 73% quarter-over-quarter.
  • 28 funds opened new Third Harmonic Bio positions in Q4 2022 and 18 closed out, a net change of +10 holders.
  • The largest Third Harmonic Bio buyer in Q4 2022 was Stonepine Capital Management, an estimated $33.7M added.
  • The largest Third Harmonic Bio seller in Q4 2022 was RA Capital Management, an estimated $49.2M sold.

Based on aggregated 13F filings for Q4 2022.