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Tenax Therapeutics
TENX

48 hedge funds and large institutions have $84.8M invested in Tenax Therapeutics in 2025 Q4 according to their latest regulatory filings, with 19 funds opening new positions, 12 increasing their positions, 3 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

300% more repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 3

280% more first-time investments, than exits

New positions opened: 19 | Existing positions closed: 5

136% more capital invested

Capital invested by funds: $35.9M → $84.8M (+$48.9M)

41% more funds holding

Funds holding: 34 → 48 (+14)

8.03% more ownership

Funds ownership: 103.47% → 111.5% (+8%)

Holders
48
Holders Change
+14
Holders Change %
+41.18%
% of All Funds
0.58%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
19
Increased
12
Reduced
3
Closed
5
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
PA
Perceptive Advisors
New York
+$3.82M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
+$3.68M
3
Morgan Stanley
Morgan Stanley
New York
+$3.64M
4
DP
Diadema Partners
New Jersey
+$2.12M
5
SFM
Sphera Funds Management
Israel
+$1.65M

Top Sellers

Rank Fund Capital Flow
1
VA
VR Adviser
New York
-$3.33M
2
Millennium Management
Millennium Management
New York
-$97.8K
3
VF
Virtu Financial
New York
-$92K
4
DS
DRW Securities
Illinois
-$80K
5
TRCT
Tower Research Capital (TRC)
New York
-$2.63K
Name Holding Trade Value Shares
Change 		Change in
Stake
IC
1
Ikarian Capital
Texas
$11.8M – – –
Morgan Stanley
2
Morgan Stanley
New York
$7.27M +$3.64M +418,047 +234%
PA
3
Perceptive Advisors
New York
$5.35M +$3.82M +439,142 New
SL
4
Siren LLC
Connecticut
$5.21M +$650K +74,700 +21%
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$5.16M +$3.68M +423,415 New
RI
6
RTW Investments
New York
$4.61M – – –
BFM
7
Boothbay Fund Management
New York
$4.29M – – –
BI
8
BVF Inc
California
$4.14M – – –
Millennium Management
9
Millennium Management
New York
$3.69M -$97.8K -11,239 -4%
Marshall Wace
10
Marshall Wace
United Kingdom
$3.63M +$1.05M +120,944 +68%
Vanguard Group
11
Vanguard Group
Pennsylvania
$3.12M +$816K +93,864 +58%
DP
12
Diadema Partners
New Jersey
$2.96M +$2.12M +243,170 New
VC
13
Vivo Capital
California
$2.54M – – –
SFM
14
Sphera Funds Management
Israel
$2.32M +$1.65M +190,111 New
IHAM
15
Integral Health Asset Management
New York
$2.04M – – –
Janus Henderson Group
16
Janus Henderson Group
United Kingdom
$2.02M – – –
WP
17
Woodline Partners
California
$1.75M +$481K +55,270 +63%
Fidelity Investments
18
Fidelity Investments
Massachusetts
$1.72M +$1.23M +141,100 New
Citadel Advisors
19
Citadel Advisors
Florida
$1.58M +$750K +86,275 +199%
Renaissance Technologies
20
Renaissance Technologies
New York
$1.53M +$600K +68,979 +122%
Adage Capital Partners
21
Adage Capital Partners
Massachusetts
$1.02M – – –
VCIM
22
Velan Capital Investment Management
Georgia
$1.02M – – –
PAP
23
Persistent Asset Partners
Hong Kong
$796K +$568K +65,272 New
ACM
24
ADAR1 Capital Management
Texas
$776K +$89.1K +10,245 +19%
Geode Capital Management
25
Geode Capital Management
Massachusetts
$679K +$185K +21,274 +62%
1
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TENX Hedge Fund Activity: Q4 2025 in Review

48 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in Tenax Therapeutics (TENX) for Q4 2025, worth a combined $84.8M — up 136% from $35.9M a quarter earlier.

Buyers outnumbered sellers: 19 funds opened new TENX positions and 5 closed out — a net gain of 14 holders — while 12 added to existing stakes and 3 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $3.82M. The largest seller was VR Adviser, exiting entirely with an estimated $3.33M sold.

  • 48 institutional investors held Tenax Therapeutics (TENX) as of Q4 2025, up from 34 in Q3 2025.
  • Funds reported $84.8M of Tenax Therapeutics stock for Q4 2025, up 136% quarter-over-quarter.
  • 19 funds opened new Tenax Therapeutics positions in Q4 2025 and 5 closed out, a net change of +14 holders.
  • The largest Tenax Therapeutics buyer in Q4 2025 was Perceptive Advisors, an estimated $3.82M added.
  • The largest Tenax Therapeutics seller in Q4 2025 was VR Adviser, an estimated $3.33M sold.

Based on aggregated 13F filings for Q4 2025.