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TECX

Tectonic Therapeutic
TECX

105 hedge funds and large institutions have $288M invested in Tectonic Therapeutic in 2025 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

837% more call options, than puts

Call options by funds: $9.91M | Put options by funds: $1.06M

52% more capital invested

Capital invested by funds: $190M → $288M (+$98.2M)

46% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 24

30% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 23

9.12% more ownership

Funds ownership: 64.69% → 73.81% (+9.1%)

6% more funds holding

Funds holding: 99 → 105 (+6)

Holders
105
Holders Change
+6
Holders Change %
+6.06%
% of All Funds
1.28%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
35
Reduced
24
Closed
23
Calls
$9.91M
Puts
$1.06M
Net Calls
+$8.86M
Net Calls Change
+$5.72M

Top Buyers

1
BBA
Baker Bros. Advisors
New York
+$14.9M
2
Aberdeen Group
Aberdeen Group
United Kingdom
+$14.6M
3
O
OrbiMed
New York
+$10.7M
4
VPC
Vestal Point Capital
New York
+$6.1M
5
OM
Opaleye Management
Massachusetts
+$3.99M

Top Sellers

1
FCM
Farallon Capital Management
California
-$10M
2
TAM
TFG Asset Management
Cayman Islands
-$3.82M
3
FLAM
First Light Asset Management
Minnesota
-$3.18M
4
SC
Stempoint Capital
New York
-$2.97M
5
TCM
Tang Capital Management
California
-$2.81M
Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$58.6M +$12.3K +661 +0%
Aberdeen Group
2
Aberdeen Group
United Kingdom
$23.8M +$14.6M +785,648 +221%
B
3
Braidwell
Connecticut
$19.3M +$3.54M +190,657 +26%
BBA
4
Baker Bros. Advisors
New York
$18.8M +$14.9M +803,400 +803%
BlackRock
5
BlackRock
New York
$17.8M +$493K +26,510 +3%
5VM
6
5AM Venture Management
California
$12.7M +$1.77M +95,000 +19%
Vanguard Group
7
Vanguard Group
Pennsylvania
$12.5M +$565K +30,418 +5%
O
8
OrbiMed
New York
$12M +$10.7M +574,600 New
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$10.3M +$1.31M +70,577 +17%
VPC
10
Vestal Point Capital
New York
$6.84M +$6.1M +328,000 New
Citadel Advisors
11
Citadel Advisors
Florida
$6.63M +$357K +19,229 +6%
BG
12
Bollard Group
Massachusetts
$6.32M – – –
Millennium Management
13
Millennium Management
New York
$6.28M +$1.16M +62,650 +26%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$5.5M -$108K -5,793 -2%
PFCS
15
Pale Fire Capital SE
Czech Republic
$5.45M +$24.2K +1,300 +0.5%
PM
16
Prosight Management
Texas
$4.9M -$2.68M -144,254 -38%
OM
17
Opaleye Management
Massachusetts
$4.48M +$3.99M +214,747 New
KCM
18
Kennedy Capital Management
Missouri
$4.36M +$8.34K +449 +0.2%
State Street
19
State Street
Massachusetts
$4.36M +$810K +43,594 +26%
WP
20
Woodline Partners
California
$4.17M – – –
Squarepoint
21
Squarepoint
New York
$4.16M +$2.49M +134,211 +205%
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$3.16M +$2.82M +151,713 New
Wells Fargo
23
Wells Fargo
California
$2.51M +$333K +17,938 +18%
D.E. Shaw & Co
24
D.E. Shaw & Co
New York
$2.51M +$2.23M +120,250 New
ECM
25
ExodusPoint Capital Management
New York
$2.32M +$1.82M +98,171 +754%
1
2 3 4 5

TECX Hedge Fund Activity: Q4 2025 in Review

105 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Tectonic Therapeutic (TECX) for Q4 2025, worth a combined $288M — up 52% from $190M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TECX positions and 23 closed out — a net gain of 7 holders — while 35 added to existing stakes and 24 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $14.9M. The largest seller was Farallon Capital Management, exiting entirely with an estimated $10M sold.

  • 105 institutional investors held Tectonic Therapeutic (TECX) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $288M of Tectonic Therapeutic stock for Q4 2025, up 52% quarter-over-quarter.
  • 30 funds opened new Tectonic Therapeutic positions in Q4 2025 and 23 closed out, a net change of +7 holders.
  • The largest Tectonic Therapeutic buyer in Q4 2025 was Baker Bros. Advisors, an estimated $14.9M added.
  • The largest Tectonic Therapeutic seller in Q4 2025 was Farallon Capital Management, an estimated $10M sold.

Based on aggregated 13F filings for Q4 2025.