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TECX

Tectonic Therapeutic
TECX

105 hedge funds and large institutions have $288M invested in Tectonic Therapeutic in 2025 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

837% more call options, than puts

Call options by funds: $9.91M | Put options by funds: $1.06M

52% more capital invested

Capital invested by funds: $190M → $288M (+$98.2M)

46% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 24

30% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 23

9.12% more ownership

Funds ownership: 64.69% → 73.81% (+9.1%)

6% more funds holding

Funds holding: 99 → 105 (+6)

Holders
105
Holders Change
+6
Holders Change %
+6.06%
% of All Funds
1.28%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
35
Reduced
24
Closed
23
Calls
$9.91M
Puts
$1.06M
Net Calls
+$8.86M
Net Calls Change
+$5.72M

Top Buyers

Rank Fund Capital Flow
1
BBA
Baker Bros. Advisors
New York
+$14.9M
2
Aberdeen Group
Aberdeen Group
United Kingdom
+$14.6M
3
O
OrbiMed
New York
+$10.7M
4
VPC
Vestal Point Capital
New York
+$6.1M
5
OM
Opaleye Management
Massachusetts
+$3.99M

Top Sellers

Rank Fund Capital Flow
1
FCM
Farallon Capital Management
California
-$10M
2
TAM
TFG Asset Management
Cayman Islands
-$3.82M
3
FLAM
First Light Asset Management
Minnesota
-$3.18M
4
SC
Stempoint Capital
New York
-$2.97M
5
TCM
Tang Capital Management
California
-$2.81M
Name Holding Trade Value Shares
Change 		Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$1.97M -$191K -10,298 -10%
Goldman Sachs
27
Goldman Sachs
New York
$1.93M -$77.4K -4,163 -4%
KK
28
Kotler Kevin
$1.67M +$1.49M +80,000 New
DMKJ
29
David M. Knott Jr
$1.54M – – –
Northern Trust
30
Northern Trust
Illinois
$1.51M -$204K -10,976 -13%
Connor, Clark & Lunn Investment Management (CC&L)
31
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.49M +$516K +27,772 +63%
GCP
32
GSA Capital Partners
United Kingdom
$1.32M +$1.18M +63,276 New
Raymond James Financial
33
Raymond James Financial
Florida
$1.14M +$49.6K +2,670 +5%
PHS
34
PFM Health Sciences
California
$891K +$794K +42,724 New
SAM
35
Sectoral Asset Management
Quebec, Canada
$881K -$2.8M -150,515 -78%
JF
36
Jump Financial
Illinois
$824K +$734K +39,500 New
SSA
37
Schonfeld Strategic Advisors
New York
$816K +$727K +39,109 New
Wellington Management Group
38
Wellington Management Group
Massachusetts
$780K +$316 +17 +0%
AC
39
Aldebaran Capital
Indiana
$779K -$21.4K -1,149 -3%
Charles Schwab
40
Charles Schwab
California
$677K +$1.91K +103 +0.3%
UBS Group
41
UBS Group
Switzerland
$651K -$655K -35,245 -53%
Marshall Wace
42
Marshall Wace
United Kingdom
$645K +$109K +5,842 +23%
ACM
43
ADAR1 Capital Management
Texas
$626K -$483K -26,000 -46%
BC
44
BIT Capital
Germany
$626K +$557K +30,000 New
MCM
45
Monimus Capital Management
New Jersey
$555K +$50.2K +2,700 +11%
Bank of New York Mellon
46
Bank of New York Mellon
New York
$539K -$5.11K -275 -1%
Barclays
47
Barclays
United Kingdom
$468K +$83K +4,467 +25%
ACM
48
Aquatic Capital Management
Illinois
$464K +$414K +22,262 New
Jane Street
49
Jane Street
New York
$403K -$175K -9,399 -33%
A
50
AlphaQuest
New York
$379K +$202K +10,888 +149%
1
2
3 4 5

TECX Hedge Fund Activity: Q4 2025 in Review

105 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Tectonic Therapeutic (TECX) for Q4 2025, worth a combined $288M — up 52% from $190M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new TECX positions and 23 closed out — a net gain of 7 holders — while 35 added to existing stakes and 24 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $14.9M. The largest seller was Farallon Capital Management, exiting entirely with an estimated $10M sold.

  • 105 institutional investors held Tectonic Therapeutic (TECX) as of Q4 2025, up from 99 in Q3 2025.
  • Funds reported $288M of Tectonic Therapeutic stock for Q4 2025, up 52% quarter-over-quarter.
  • 30 funds opened new Tectonic Therapeutic positions in Q4 2025 and 23 closed out, a net change of +7 holders.
  • The largest Tectonic Therapeutic buyer in Q4 2025 was Baker Bros. Advisors, an estimated $14.9M added.
  • The largest Tectonic Therapeutic seller in Q4 2025 was Farallon Capital Management, an estimated $10M sold.

Based on aggregated 13F filings for Q4 2025.