|
1
|
MPM Asset Management
Boston,
Massachusetts
|
$31.4M
|
–
|
–
|
–
|
|
|
2
|
MPM BioImpact
Boston,
Massachusetts
|
$26.1M
|
–
|
–
|
–
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$13.7M
|
-$390K
|
-31,900
|
-2%
|
|
|
4
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$10.5M
|
+$1.14M
|
+92,887
|
+7%
|
|
|
5
|
|
$6.92M
|
+$47.6K
|
+3,888
|
+0.4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.77M
|
+$107K
|
+8,748
|
+2%
|
|
|
7
|
|
$3.1M
|
–
|
–
|
–
|
|
|
8
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$2.5M
|
–
|
–
|
–
|
|
|
9
|
|
$1.75M
|
+$223K
|
+18,197
|
+9%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$1.57M
|
-$2.41K
|
-197
|
-0.1%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$1.48M
|
+$193K
|
+15,785
|
+9%
|
|
|
12
|
Northern Trust
Chicago,
Illinois
|
$1.19M
|
+$76.8K
|
+6,272
|
+4%
|
|
|
13
|
Victory Capital Management
San Antonio,
Texas
|
$652K
|
-$26.8K
|
-2,191
|
-3%
|
|
|
14
|
Charles Schwab
San Francisco,
California
|
$629K
|
+$21.9K
|
+1,786
|
+2%
|
|
|
15
|
DAFNA Capital Management
Los Angeles,
California
|
$610K
|
+$964K
|
+78,786
|
New
|
|
|
16
|
Millennium Management
New York
|
$550K
|
+$256K
|
+20,886
|
+42%
|
|
|
17
|
Renaissance Technologies
New York
|
$397K
|
+$628K
|
+51,300
|
New
|
|
|
18
|
SVB Wealth
Boston,
Massachusetts
|
$379K
|
–
|
–
|
–
|
|
|
19
|
Bank of New York Mellon
New York
|
$321K
|
–
|
–
|
–
|
|
|
20
|
Parametric Portfolio Associates
Seattle,
Washington
|
$302K
|
+$76.6K
|
+6,261
|
+19%
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$295K
|
-$13.2K
|
-1,080
|
-3%
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$288K
|
+$1.5K
|
+123
|
+0.3%
|
|
|
23
|
Soleus Capital Management
Greenwich,
Connecticut
|
$237K
|
+$375K
|
+30,624
|
New
|
|
|
24
|
IndexIQ Advisors
New York
|
$220K
|
+$348K
|
+28,431
|
New
|
|
|
25
|
First Trust Advisors
Wheaton,
Illinois
|
$201K
|
-$61.7K
|
-5,038
|
-16%
|
|
