|
1
|
|
$196M
|
-$9.84M
|
-216,659
|
-6%
|
|
|
2
|
|
$179M
|
-$7.99M
|
-175,937
|
-5%
|
|
|
3
|
Paradigm Biocapital Advisors
New York
|
$140M
|
+$4.15M
|
+91,451
|
+4%
|
|
|
4
|
Jennison Associates
New York
|
$138M
|
+$14.6M
|
+321,552
|
+15%
|
|
|
5
|
Tang Capital Management
San Diego,
California
|
$125M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$117M
|
+$810K
|
+17,839
|
+0.9%
|
|
|
7
|
|
$109M
|
-$10.9M
|
-239,517
|
-11%
|
|
|
8
|
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
$106M
|
+$86.7M
|
+1,909,228
|
New
|
|
|
9
|
Frazier Life Sciences Management
Palo Alto,
California
|
$87.9M
|
–
|
–
|
–
|
|
|
10
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$70.9M
|
+$31.1M
|
+685,111
|
+115%
|
|
|
11
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$63.5M
|
+$253K
|
+5,565
|
+0.5%
|
|
|
12
|
|
$51.6M
|
+$11.4M
|
+250,018
|
+37%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$50.8M
|
+$794K
|
+17,477
|
+2%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$46.5M
|
+$137K
|
+3,014
|
+0.4%
|
|
|
15
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$45.2M
|
+$10M
|
+221,034
|
+37%
|
|
|
16
|
Artisan Partners
Milwaukee,
Wisconsin
|
$38.3M
|
-$805K
|
-17,719
|
-2%
|
|
|
17
|
Millennium Management
New York
|
$35.7M
|
+$19.1M
|
+421,495
|
+189%
|
|
|
18
|
Ikarian Capital
Dallas,
Texas
|
$33.6M
|
-$19.2M
|
-422,588
|
-41%
|
|
|
19
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$31.6M
|
-$771K
|
-16,974
|
-3%
|
|
|
20
|
Cormorant Asset Management
Boston,
Massachusetts
|
$27.7M
|
–
|
–
|
–
|
|
|
21
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$25.5M
|
+$10.1M
|
+221,458
|
+93%
|
|
|
22
|
Jefferies Financial Group
New York
|
$23.3M
|
–
|
–
|
–
|
|
|
23
|
Gilder Gagnon Howe & Co
New York
|
$22.4M
|
+$18M
|
+397,190
|
+5,636%
|
|
|
24
|
|
$20.2M
|
+$8.33M
|
+183,449
|
+101%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$19.8M
|
+$1.82M
|
+40,061
|
+13%
|
|
