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Synlogic
SYBX

Overview Fund Activity

62 hedge funds and large institutions have $105M invested in Synlogic in 2021 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 16 increasing their positions, 13 reducing their positions, and 17 closing their positions.

Holders
62
Holders Change
-7
Holders Change %
-10.14%
% of All Funds
0.96%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
10
Increased
16
Reduced
13
Closed
17
Calls
$4K
Puts
$14K
Net Calls
-$10K
Net Calls Change
+$19K

Top Buyers

1
OM
1
Opaleye Management
Massachusetts
$2.06M
2
Alyeska Investment Group
2
Alyeska Investment Group
Illinois
$6.09M
3
HCA
3
Harbor Capital Advisors
Illinois
$1.06M
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$25.3M
5
Millennium Management
5
Millennium Management
New York
$711K

Top Sellers

1
LGM
1
Logos Global Management
California
$0
2
MS
2
Maven Securities
Jersey
$0
3
IC
3
Ikarian Capital
Texas
$1.17M
4
GGHC
4
Gilder Gagnon Howe & Co
New York
$0
5
MIM
5
Monashee Investment Management
Massachusetts
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$25.3M 10,456,385 +350,084 +3%
RCM
2
RA Capital Management
Massachusetts
$16.1M 6,666,666 – –
O
3
OrbiMed
New York
$14.6M 6,029,995 – –
NMC
4
NEA Management Company
Maryland
$10.2M 4,229,410 – –
AVAI
5
Atlas Venture Associates IX
Massachusetts
$6.42M 2,651,963 – –
Alyeska Investment Group
6
Alyeska Investment Group
Illinois
$6.09M 2,516,706 +460,413 +22%
Vanguard Group
7
Vanguard Group
Pennsylvania
$5.45M 2,252,000 +32,314 +1%
SCM
8
Stonepine Capital Management
Oregon
$2.58M 1,064,135 +64,135 +6%
OM
9
Opaleye Management
Massachusetts
$2.06M 850,000 +850,000 New
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$1.53M 632,168 -81,721 -11%
SI
11
Sofinnova Investments
California
$1.39M 574,972 – –
LP
12
LMR Partners
United Kingdom
$1.33M 550,000 +50,000 +10%
IC
13
Ikarian Capital
Texas
$1.17M 483,818 -305,000 -39%
RA
14
Royce & Associates
New York
$1.17M 484,041 – –
HCA
15
Harbor Capital Advisors
Illinois
$1.06M 437,550 +437,550 New
BlackRock
16
BlackRock
New York
$971K 401,129 +28,170 +8%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$930K 384,200 -18,700 -5%
Two Sigma Investments
18
Two Sigma Investments
New York
$838K 346,107 -101,543 -23%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$796K 328,986 +20,479 +7%
Millennium Management
20
Millennium Management
New York
$711K 293,859 +192,033 +189%
BCM
21
Bridgeway Capital Management
Texas
$678K 280,000 +100,000 +56%
AICPI
22
ABG Innovation Capital Partners III
Hong Kong
$498K 205,906 – –
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$322K 132,916 +83,329 +168%
Franklin Resources
24
Franklin Resources
California
$245K 101,443 -257 -0.3%
State Street
25
State Street
Massachusetts
$209K 86,256 – –
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