|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$341M
|
+$120M
|
+2,099,889
|
+53%
|
|
|
2
|
|
$340M
|
–
|
–
|
–
|
|
|
3
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$273M
|
–
|
–
|
–
|
|
|
4
|
Perceptive Advisors
New York
|
$256M
|
-$18.4M
|
-321,919
|
-7%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$163M
|
+$1.07M
|
+18,674
|
+0.7%
|
|
|
6
|
|
$130M
|
-$3.34M
|
-58,373
|
-2%
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$117M
|
–
|
–
|
–
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$106M
|
+$74.3M
|
+1,299,214
|
+225%
|
|
|
9
|
Driehaus Capital Management
Chicago,
Illinois
|
$104M
|
+$3.08M
|
+53,897
|
+3%
|
|
|
10
|
Bank of America
Charlotte,
North Carolina
|
$91.9M
|
+$6.47M
|
+113,114
|
+7%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$90.1M
|
+$15.8M
|
+276,779
|
+21%
|
|
|
12
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$75.5M
|
+$13M
|
+228,039
|
+21%
|
|
|
13
|
|
$53.5M
|
+$21.4M
|
+374,584
|
+65%
|
|
|
14
|
|
$48M
|
–
|
–
|
–
|
|
|
15
|
Victory Capital Management
San Antonio,
Texas
|
$44.1M
|
+$449K
|
+7,843
|
+1%
|
|
|
16
|
Marshall Wace
London,
United Kingdom
|
$39.8M
|
+$17M
|
+297,078
|
+73%
|
|
|
17
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$36.9M
|
+$237K
|
+4,145
|
+0.6%
|
|
|
18
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$35.8M
|
-$3.45M
|
-60,207
|
-9%
|
|
|
19
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$30M
|
-$581K
|
-10,152
|
-2%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$29M
|
+$1.2M
|
+20,970
|
+4%
|
|
|
21
|
Sphera Funds Management
Tel Aviv,
Israel
|
$26M
|
+$6.72M
|
+117,459
|
+34%
|
|
|
22
|
Phoenix Financial
Givatayim,
Israel
|
$22.6M
|
+$5.14M
|
+89,890
|
+29%
|
|
|
23
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$22.3M
|
+$631K
|
+11,032
|
+3%
|
|
|
24
|
EcoR1 Capital
San Francisco,
California
|
$18.4M
|
+$18.6M
|
+325,881
|
New
|
|
|
25
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$17.8M
|
+$195K
|
+3,401
|
+1%
|
|
