|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$48.2M
|
+$20.7M
|
+1,330,718
|
+73%
|
|
|
2
|
Consonance Capital Management
New York
|
$39.9M
|
+$4M
|
+256,806
|
+11%
|
|
|
3
|
Adage Capital Partners
Boston,
Massachusetts
|
$27.4M
|
+$5.57M
|
+357,143
|
+25%
|
|
|
4
|
|
$24M
|
+$2.58M
|
+165,245
|
+12%
|
|
|
5
|
Lyon Street Capital
Sausalito,
California
|
$19M
|
+$6.43M
|
+412,203
|
+50%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$17M
|
+$2.44M
|
+156,242
|
+16%
|
|
|
7
|
Eventide Asset Management
Boston,
Massachusetts
|
$16.6M
|
–
|
–
|
–
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$13.7M
|
+$8.21M
|
+526,760
|
+143%
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$8.95M
|
+$9.12M
|
+584,873
|
New
|
|
|
10
|
|
$8.64M
|
+$223K
|
+14,275
|
+3%
|
|
|
11
|
Avoro Capital Advisors
New York
|
$8.02M
|
+$8.17M
|
+524,321
|
New
|
|
|
12
|
Nexthera Capital
New York
|
$8.01M
|
+$8.16M
|
+523,624
|
New
|
|
|
13
|
International Biotechnology Trust
London,
United Kingdom
|
$7.52M
|
–
|
–
|
–
|
|
|
14
|
|
$6.12M
|
+$3.12M
|
+200,000
|
+100%
|
|
|
15
|
Polar Capital
London,
United Kingdom
|
$5.71M
|
+$5.82M
|
+373,285
|
New
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$5.17M
|
+$663K
|
+42,537
|
+14%
|
|
|
17
|
Baker Bros. Advisors
New York
|
$4.4M
|
-$5.39M
|
-345,670
|
-55%
|
|
|
18
|
|
$3.83M
|
+$898K
|
+57,588
|
+30%
|
|
|
19
|
Point72 Asset Management
Stamford,
Connecticut
|
$3.83M
|
+$3.9M
|
+250,000
|
New
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$3.55M
|
+$721K
|
+46,280
|
+25%
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.32M
|
–
|
–
|
–
|
|
|
22
|
C WorldWide Group
Copenhagen,
Denmark
|
$2.6M
|
-$397K
|
-25,442
|
-13%
|
|
|
23
|
Bank of New York Mellon
New York
|
$1.74M
|
+$199K
|
+12,765
|
+13%
|
|
|
24
|
|
$1.38M
|
+$234K
|
+15,008
|
+20%
|
|
|
25
|
TIAA CREF Investment Management
New York
|
$1.36M
|
+$596K
|
+38,237
|
+76%
|
|
