Scholar Rock
SRRK
274 hedge funds and large institutions have $5.44B invested in Scholar Rock in 2025 Q4 according to their latest regulatory filings, with 77 funds opening new positions, 95 increasing their positions, 68 reducing their positions, and 37 closing their positions.
108% more first-time investments, than exits
New positions opened: 77 | Existing positions closed: 37
40% more repeat investments, than reductions
Existing positions increased: 95 | Existing positions reduced: 68
26% more capital invested
Capital invested by funds: $4.32B → $5.44B (+$1.12B)
14% more funds holding
Funds holding: 241 → 274 (+33)
0.41% more ownership
Funds ownership: 120.67% → 121.08% (+0.41%)
0% more funds holding in top 10
Funds holding in top 10: 7 → 7 (0)
24% less call options, than puts
Call options by funds: $23.6M | Put options by funds: $31M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OAG
Orbis Allan Gray
Hamilton,
Bermuda
|
+$117M |
| 2 |
SL
Siren LLC
Greenwich,
Connecticut
|
+$59.1M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$51.3M |
| 4 |
RG
Redmile Group
San Francisco,
California
|
+$49.4M |
| 5 |
SB
Samsara BioCapital
Palo Alto,
California
|
+$48.2M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Adage Capital Partners
Boston,
Massachusetts
|
-$72.7M |
| 2 |
FFM
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
-$67.9M |
| 3 |
Janus Henderson Group
London,
|
-$46.5M |
| 4 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$43.5M |
| 5 |
Holocene Advisors
New York
|
-$40.3M |
SRRK Hedge Fund Activity: Q4 2025 in Review
274 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Scholar Rock (SRRK) for Q4 2025, worth a combined $5.44B — up 26% from $4.32B a quarter earlier.
Buyers outnumbered sellers: 77 funds opened new SRRK positions and 37 closed out — a net gain of 40 holders — while 95 added to existing stakes and 68 trimmed.
The largest buyer was Orbis Allan Gray, adding an estimated $117M. The largest seller was Adage Capital Partners, exiting entirely with an estimated $72.7M sold.
- 274 institutional investors held Scholar Rock (SRRK) as of Q4 2025, up from 241 in Q3 2025.
- Funds reported $5.44B of Scholar Rock stock for Q4 2025, up 26% quarter-over-quarter.
- 77 funds opened new Scholar Rock positions in Q4 2025 and 37 closed out, a net change of +40 holders.
- The largest Scholar Rock buyer in Q4 2025 was Orbis Allan Gray, an estimated $117M added.
- The largest Scholar Rock seller in Q4 2025 was Adage Capital Partners, an estimated $72.7M sold.
Based on aggregated 13F filings for Q4 2025.