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Scholar Rock

224 hedge funds and large institutions have $4.51B invested in Scholar Rock in 2024 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 70 increasing their positions, 59 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

535% more capital invested

Capital invested by funds: $710M → $4.51B (+$3.8B)

350% more funds holding in top 10

Funds holding in top 10: 29 (+7)

325% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 20

44% more call options, than puts

Call options by funds: $75.1M | Put options by funds: $52.2M

39% more funds holding

Funds holding: 161224 (+63)

19% more repeat investments, than reductions

Existing positions increased: 70 | Existing positions reduced: 59

0.75% more ownership

Funds ownership: 110.71%111.47% (+0.75%)

Holders
224
Holders Change
+63
Holders Change %
+39.13%
% of All Funds
2.95%
Holding in Top 10
9
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+350%
% of All Funds
0.12%
New
85
Increased
70
Reduced
59
Closed
20
Calls
$75.1M
Puts
$52.2M
Net Calls
+$22.9M
Net Calls Change
+$24.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$32.3M +$4.1M +125,904 +20%
Capital World Investors
27
Capital World Investors
California
$31.2M +$23.5M +721,957 New
RSCM
28
Rock Springs Capital Management
Maryland
$31M +$23.3M +716,782 New
D.E. Shaw & Co
29
D.E. Shaw & Co
New York
$28.8M +$15.3M +471,111 +241%
American Century Companies
30
American Century Companies
Missouri
$28.4M +$21.4M +656,967 New
Charles Schwab
31
Charles Schwab
California
$26.9M +$3.89M +119,616 +24%
CS
32
Candriam SCA
Luxembourg
$25.2M -$18.7M -573,182 -50%
Fisher Asset Management
33
Fisher Asset Management
Washington
$24M -$5.84M -179,282 -24%
DCM
34
Driehaus Capital Management
Illinois
$22.3M +$16.8M +516,005 New
OCA
35
Octagon Capital Advisors
New York
$21.1M +$15.9M +488,000 New
Lord, Abbett & Co
36
Lord, Abbett & Co
New Jersey
$20.4M +$15.3M +471,300 New
ClearBridge Investments
37
ClearBridge Investments
New York
$18.2M -$16.4M -503,011 -54%
MB
38
MPM BioImpact
Massachusetts
$18M +$13.6M +416,144 New
Morgan Stanley
39
Morgan Stanley
New York
$17.9M +$4.55M +139,865 +51%
PBA
40
Paradigm Biocapital Advisors
New York
$17.3M +$13M +400,000 New
Two Sigma Investments
41
Two Sigma Investments
New York
$17.2M -$7.21M -221,365 -36%
NNPTE
42
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$16.7M +$12.6M +385,925 New
IHAM
43
Integral Health Asset Management
New York
$16.2M +$3.26M +100,000 +36%
TD Asset Management
44
TD Asset Management
Ontario, Canada
$15.7M +$2.91M +89,470 +33%
IC
45
Ikarian Capital
Texas
$15.4M +$11.6M +357,185 New
Invesco
46
Invesco
Georgia
$13.5M +$9.43M +289,748 +1,293%
N
47
Nuveen
North Carolina
$13.2M +$3.99M +122,638 +67%
Two Sigma Advisers
48
Two Sigma Advisers
New York
$11.3M -$10.8M -330,600 -56%
Manulife (Manufacturers Life Insurance)
49
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$9.19M -$126K -3,858 -2%
Bank of New York Mellon
50
Bank of New York Mellon
New York
$8.97M +$909K +27,930 +16%

SRRK Hedge Fund Activity: Q4 2024 in Review

224 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Scholar Rock (SRRK) for Q4 2024, worth a combined $4.51B — up 535% from $710M a quarter earlier.

Buyers outnumbered sellers: 85 funds opened new SRRK positions and 20 closed out — a net gain of 65 holders — while 70 added to existing stakes and 59 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $112M. The largest seller was Siren LLC, cutting an estimated $65.4M.

  • 224 institutional investors held Scholar Rock (SRRK) as of Q4 2024, up from 161 in Q3 2024.
  • Funds reported $4.51B of Scholar Rock stock for Q4 2024, up 535% quarter-over-quarter.
  • 85 funds opened new Scholar Rock positions in Q4 2024 and 20 closed out, a net change of +65 holders.
  • The largest Scholar Rock buyer in Q4 2024 was Fidelity Investments, an estimated $112M added.
  • The largest Scholar Rock seller in Q4 2024 was Siren LLC, an estimated $65.4M sold.

Based on aggregated 13F filings for Q4 2024.