|
1
|
Vivo Capital
Palo Alto,
California
|
$42M
|
–
|
–
|
–
|
|
|
2
|
|
$32.4M
|
–
|
–
|
–
|
|
|
3
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$28.8M
|
+$5.91M
|
+295,339
|
+29%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$25.1M
|
+$6.11M
|
+305,479
|
+36%
|
|
|
5
|
Abingworth
London,
United Kingdom
|
$19M
|
+$111K
|
+5,531
|
+0.6%
|
|
|
6
|
Frazier Management
Seattle,
Washington
|
$17.6M
|
+$12M
|
+601,864
|
+297%
|
|
|
7
|
Ikarian Capital
Dallas,
Texas
|
$12.6M
|
+$568K
|
+28,378
|
+5%
|
|
|
8
|
Caxton Corporation
Princeton,
New Jersey
|
$9.71M
|
-$24.1K
|
-1,205
|
-0.3%
|
|
|
9
|
New Leaf Venture Partners
New York
|
$8.98M
|
–
|
–
|
–
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.03M
|
+$4.59M
|
+229,258
|
New
|
|
|
11
|
Sofinnova Investments
Menlo Park,
California
|
$4.53M
|
+$4.08M
|
+204,064
|
+8,163%
|
|
|
12
|
Ghost Tree Capital
New York
|
$4.38M
|
–
|
–
|
–
|
|
|
13
|
Opaleye Management
Boston,
Massachusetts
|
$3.63M
|
+$5.56K
|
+278
|
+0.2%
|
|
|
14
|
Silverarc Capital Management
Boston,
Massachusetts
|
$3.58M
|
+$484K
|
+24,181
|
+17%
|
|
|
15
|
Renaissance Technologies
New York
|
$2.31M
|
-$18K
|
-900
|
-0.8%
|
|
|
16
|
Millennium Management
New York
|
$2.15M
|
-$160K
|
-8,003
|
-8%
|
|
|
17
|
Sio Capital Management
New York
|
$2.09M
|
+$44K
|
+2,198
|
+2%
|
|
|
18
|
Pura Vida Investments
New York
|
$1.61M
|
-$26.7K
|
-1,334
|
-2%
|
|
|
19
|
Bridgeway Capital Management
Houston,
Texas
|
$1.33M
|
–
|
–
|
–
|
|
|
20
|
Boothbay Fund Management
New York
|
$1.27M
|
-$139K
|
-6,930
|
-11%
|
|
|
21
|
Nan Fung Group Holdings
Kai Tak,
Hong Kong
|
$1.16M
|
-$1.56M
|
-78,000
|
-60%
|
|
|
22
|
Two Sigma Advisers
New York
|
$935K
|
+$853K
|
+42,656
|
New
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$851K
|
+$5.4K
|
+270
|
+0.7%
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$506K
|
+$99.4K
|
+4,968
|
+27%
|
|
|
25
|
Two Sigma Investments
New York
|
$491K
|
+$448K
|
+22,401
|
New
|
|
