|
1
|
|
$87.2M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$42.8M
|
-$9.85M
|
-399,419
|
-9%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$17.4M
|
–
|
–
|
–
|
|
|
4
|
Boxer Capital
San Diego,
California
|
$16.7M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$16.7M
|
+$16.6M
|
+673,544
|
+68%
|
|
|
6
|
Wasatch Advisors
Salt Lake City,
Utah
|
$14.3M
|
+$19.4M
|
+786,148
|
+122%
|
|
|
7
|
|
$12.3M
|
+$8.59M
|
+348,296
|
+40%
|
|
|
8
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$12.2M
|
-$977K
|
-39,635
|
-3%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$11.8M
|
-$35.3M
|
-1,433,326
|
-55%
|
|
|
10
|
Millennium Management
New York
|
$9.52M
|
+$23.3M
|
+944,661
|
+10,461%
|
|
|
11
|
|
$6.37M
|
+$15.4M
|
+625,477
|
+4,730%
|
|
|
12
|
Woodline Partners
San Francisco,
California
|
$4.24M
|
+$1.17M
|
+47,630
|
+13%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$3.04M
|
+$1.99M
|
+80,750
|
+36%
|
|
|
14
|
Marshall Wace
London,
United Kingdom
|
$2.75M
|
+$6.8M
|
+275,567
|
New
|
|
|
15
|
|
$2.5M
|
+$998K
|
+40,453
|
+19%
|
|
|
16
|
PFM Health Sciences
San Francisco,
California
|
$1.88M
|
–
|
–
|
–
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$1.85M
|
+$1.48M
|
+59,849
|
+48%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$1.85M
|
-$877K
|
-35,576
|
-16%
|
|
|
19
|
5AM Venture Management
San Francisco,
California
|
$1.69M
|
+$4.19M
|
+169,748
|
New
|
|
|
20
|
Marshall Wace North America
New York
|
$1.62M
|
+$4M
|
+162,183
|
New
|
|
|
21
|
Schroder Investment Management Group
London,
United Kingdom
|
$1.56M
|
-$188K
|
-7,619
|
-5%
|
|
|
22
|
Two Sigma Investments
New York
|
$1.5M
|
+$3.71M
|
+150,572
|
New
|
|
|
23
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$1.5M
|
+$1.23M
|
+50,000
|
+50%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$1.39M
|
+$1.31M
|
+53,301
|
+62%
|
|
|
25
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$1.19M
|
+$2.95M
|
+119,551
|
New
|
|
