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ARS Pharmaceuticals

188 hedge funds and large institutions have $840M invested in ARS Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 43 funds opening new positions, 69 increasing their positions, 44 reducing their positions, and 42 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more call options, than puts

Call options by funds: $13.5M | Put options by funds: $7.46M

57% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 44

2% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 42

1% more funds holding

Funds holding: 187188 (+1)

1.43% less ownership

Funds ownership: 86.06%84.63% (-1.4%)

43% less capital invested

Capital invested by funds: $1.48B → $840M (-$635M)

88% less funds holding in top 10

Funds holding in top 10: 81 (-7)

Holders
188
Holders Change
+1
Holders Change %
+0.53%
% of All Funds
2.47%
Holding in Top 10
1
Holding in Top 10 Change
-7
Holding in Top 10 Change %
-87.5%
% of All Funds
0.01%
New
43
Increased
69
Reduced
44
Closed
42
Calls
$13.5M
Puts
$7.46M
Net Calls
+$6.02M
Net Calls Change
-$1.06M
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$109M
O
2
OrbiMed
New York
$83.3M
DM
3
Deerfield Management
New York
$75.4M -$31.9M -2,220,696 -23%
BlackRock
4
BlackRock
New York
$48.6M +$5.85M +407,863 +9%
RCMNY
5
Rubric Capital Management (New York)
New York
$45.2M +$46M +3,205,122 +248%
SOCM
6
SR One Capital Management
Pennsylvania
$40.3M
Vanguard Group
7
Vanguard Group
Pennsylvania
$35.2M +$3.41M +237,630 +7%
Aberdeen Group
8
Aberdeen Group
United Kingdom
$31.1M +$22.9M +1,594,447 +106%
State Street
9
State Street
Massachusetts
$29.1M +$10.1M +700,763 +32%
AllianceBernstein
10
AllianceBernstein
Tennessee
$26.6M -$17M -1,183,682 -31%
Franklin Resources
11
Franklin Resources
California
$24.1M +$8.17M +569,257 +31%
CC
12
Casdin Capital
New York
$16.1M +$23M +1,600,000 New
Citadel Advisors
13
Citadel Advisors
Florida
$15.9M -$9.42M -656,143 -29%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$15.1M +$2.34M +163,230 +12%
SCA
15
Southpoint Capital Advisors
New York
$15.1M -$3M -209,069 -12%
Goldman Sachs
16
Goldman Sachs
New York
$13.3M -$1.99M -138,573 -9%
MB
17
MPM BioImpact
Massachusetts
$13.1M
BAMCO Inc
18
BAMCO Inc
New York
$12.7M +$17.6M +1,228,532 +3,071%
Janney Montgomery Scott
19
Janney Montgomery Scott
Pennsylvania
$12.2M +$8.92M +621,595 +105%
Qube Research & Technologies (QRT)
20
Qube Research & Technologies (QRT)
United Kingdom
$10.4M +$14.9M +1,034,798 New
EP
21
Eversept Partners
New York
$9.81M +$14M +976,511 New
LCS
22
Levin Capital Strategies
New York
$7.68M +$6.82M +475,147 +164%
Raymond James Financial
23
Raymond James Financial
Florida
$7.6M +$1.19M +82,977 +12%
Fidelity Investments
24
Fidelity Investments
Massachusetts
$7.46M -$11.8M -824,502 -53%
Morgan Stanley
25
Morgan Stanley
New York
$7.04M +$4.55M +316,798 +83%

SPRY Hedge Fund Activity: Q3 2025 in Review

188 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in ARS Pharmaceuticals (SPRY) for Q3 2025, worth a combined $840M — down 43% from $1.48B a quarter earlier.

Buyers outnumbered sellers: 43 funds opened new SPRY positions and 42 closed out — a net gain of 1 holder — while 69 added to existing stakes and 44 trimmed.

The largest buyer was Rubric Capital Management (New York), adding an estimated $46M. The largest seller was Deerfield Management, cutting an estimated $31.9M.

  • 188 institutional investors held ARS Pharmaceuticals (SPRY) as of Q3 2025, up from 187 in Q2 2025.
  • Funds reported $840M of ARS Pharmaceuticals stock for Q3 2025, down 43% quarter-over-quarter.
  • 43 funds opened new ARS Pharmaceuticals positions in Q3 2025 and 42 closed out, a net change of +1 holder.
  • The largest ARS Pharmaceuticals buyer in Q3 2025 was Rubric Capital Management (New York), an estimated $46M added.
  • The largest ARS Pharmaceuticals seller in Q3 2025 was Deerfield Management, an estimated $31.9M sold.

Based on aggregated 13F filings for Q3 2025.