SOPHiA GENETICS
SOPH
40 hedge funds and large institutions have $84.3M invested in SOPHiA GENETICS in 2025 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 11 increasing their positions, 8 reducing their positions, and 3 closing their positions.
267% more first-time investments, than exits
New positions opened: 11 | Existing positions closed: 3
65% more capital invested
Capital invested by funds: $51.2M → $84.3M (+$33.1M)
38% more repeat investments, than reductions
Existing positions increased: 11 | Existing positions reduced: 8
25% more funds holding
Funds holding: 32 → 40 (+8)
1.43% more ownership
Funds ownership: 24.78% → 26.21% (+1.4%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
AWA
Alta Wealth Advisors
Woburn,
Massachusetts
|
+$4.84M |
| 2 |
ACM
Archon Capital Management
Seattle,
Washington
|
+$363K |
| 3 |
FIA
FNY Investment Advisers
New York
|
+$154K |
| 4 |
TSW
Thompson Siegel & Walmsley
Richmond,
Virginia
|
+$102K |
| 5 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$63.5K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Millennium Management
New York
|
-$1.23M |
| 2 |
Ensign Peak Advisors
Salt Lake City,
Utah
|
-$188K |
| 3 |
RI
Ridgewood Investments
Springfield,
New Jersey
|
-$107K |
| 4 |
Citadel Advisors
Miami,
Florida
|
-$92.1K |
| 5 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
-$34.4K |
SOPH Hedge Fund Activity: Q3 2025 in Review
40 of the 7,622 institutional investors tracked by Wall St. Rank reported a position in SOPHiA GENETICS (SOPH) for Q3 2025, worth a combined $84.3M — up 65% from $51.2M a quarter earlier.
Buyers outnumbered sellers: 11 funds opened new SOPH positions and 3 closed out — a net gain of 8 holders — while 11 added to existing stakes and 8 trimmed.
The largest buyer was Alta Wealth Advisors, opening a new position worth an estimated $4.84M. The largest seller was Millennium Management, cutting an estimated $1.23M.
- 40 institutional investors held SOPHiA GENETICS (SOPH) as of Q3 2025, up from 32 in Q2 2025.
- Funds reported $84.3M of SOPHiA GENETICS stock for Q3 2025, up 65% quarter-over-quarter.
- 11 funds opened new SOPHiA GENETICS positions in Q3 2025 and 3 closed out, a net change of +8 holders.
- The largest SOPHiA GENETICS buyer in Q3 2025 was Alta Wealth Advisors, an estimated $4.84M added.
- The largest SOPHiA GENETICS seller in Q3 2025 was Millennium Management, an estimated $1.23M sold.
Based on aggregated 13F filings for Q3 2025.