SOPHiA GENETICS
SOPH
71 hedge funds and large institutions have $213M invested in SOPHiA GENETICS in 2026 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 16 increasing their positions, 16 reducing their positions, and 4 closing their positions.
1,767% more capital inflows, than outflows
Capital inflows: $67.1M | Capital outflows: $3.6M
550% more first-time investments, than exits
New positions opened: 26 | Existing positions closed: 4
45% more funds holding
Funds holding: 49 → 71 (+22)
8.4% more ownership
Funds ownership: 35.51% → 43.91% (+8.4%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0% more repeat investments, than reductions
Existing positions increased: 16 | Existing positions reduced: 16
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
ACM
AIGH Capital Management
Baltimore,
Maryland
|
+$20.1M |
| 2 |
Ameriprise
Minneapolis,
Minnesota
|
+$11.2M |
| 3 |
AIC
AWM Investment Company
New York
|
+$8.63M |
| 4 |
Royce & Associates
New York
|
+$7.94M |
| 5 |
Silvercrest Asset Management
New York
|
+$7.25M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Soleus Capital Management
Greenwich,
Connecticut
|
-$1.45M |
| 2 |
SEI Investments
Oaks,
Pennsylvania
|
-$978K |
| 3 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
-$244K |
| 4 |
Rathbones Group
Liverpool,
United Kingdom
|
-$188K |
| 5 |
EIM
Essex Investment Management
Boston,
Massachusetts
|
-$149K |
SOPH Hedge Fund Activity: Q2 2026 in Review
71 of the 8,354 institutional investors tracked by Wall St. Rank reported a position in SOPHiA GENETICS (SOPH) for Q2 2026, worth a combined $213M — up 77% from $120M a quarter earlier.
Buyers outnumbered sellers: 26 funds opened new SOPH positions and 4 closed out — a net gain of 22 holders — while 16 added to existing stakes and 16 trimmed.
The largest buyer was AIGH Capital Management, opening a new position worth an estimated $20.1M. The largest seller was Soleus Capital Management, cutting an estimated $1.45M.
- 71 institutional investors held SOPHiA GENETICS (SOPH) as of Q2 2026, up from 49 in Q1 2026.
- Funds reported $213M of SOPHiA GENETICS stock for Q2 2026, up 77% quarter-over-quarter.
- 26 funds opened new SOPHiA GENETICS positions in Q2 2026 and 4 closed out, a net change of +22 holders.
- The largest SOPHiA GENETICS buyer in Q2 2026 was AIGH Capital Management, an estimated $20.1M added.
- The largest SOPHiA GENETICS seller in Q2 2026 was Soleus Capital Management, an estimated $1.45M sold.
Based on aggregated 13F filings for Q2 2026.