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Senti Biosciences Holdings

15 hedge funds and large institutions have $5.84M invested in Senti Biosciences Holdings in 2025 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 4 increasing their positions, 2 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more repeat investments, than reductions

Existing positions increased: 4 | Existing positions reduced: 2

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

1.06% less ownership

Funds ownership: 22.41%21.35% (-1.1%)

6% less funds holding

Funds holding: 1615 (-1)

20% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 5

29% less capital invested

Capital invested by funds: $8.27M → $5.84M (-$2.43M)

Holders
15
Holders Change
-1
Holders Change %
-6.25%
% of All Funds
0.18%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
4
Increased
4
Reduced
2
Closed
5
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
NMC
1
NEA Management Company
Maryland
$3.93M
NCM
2
Nantahala Capital Management
Connecticut
$924K
Vanguard Group
3
Vanguard Group
Pennsylvania
$654K +$22.3K +12,624 +2%
Geode Capital Management
4
Geode Capital Management
Massachusetts
$151K -$14.2K -8,041 -5%
VF
5
Virtu Financial
New York
$46K +$78.5K +44,409 New
Jane Street
6
Jane Street
New York
$40K +$67.9K +38,427 New
MG
7
MSOP GP
California
$37.2K +$63.2K +35,737 New
BlackRock
8
BlackRock
New York
$24.3K +$1.38K +780 +3%
Northern Trust
9
Northern Trust
Illinois
$17.4K +$827 +468 +3%
State Street
10
State Street
Massachusetts
$10.4K
UBS Group
11
UBS Group
Switzerland
$4.71K +$8.01K +4,529 New
TRCT
12
Tower Research Capital (TRC)
New York
$3.55K +$2.97K +1,681 +97%
SS
13
SBI Securities
Japan
$349
Morgan Stanley
14
Morgan Stanley
New York
$166
Bank of America
15
Bank of America
North Carolina
$78 -$663 -375 -83%
8GI
16
8VC GP I
Texas
-$358K -253,755 Closed
Citadel Advisors
17
Citadel Advisors
Florida
-$117K -82,753 Closed
XT
18
XTX Topco
Cayman Islands
-$37.5K -26,567 Closed
Two Sigma Investments
19
Two Sigma Investments
New York
-$22.5K -15,968 Closed
Citigroup
20
Citigroup
New York
-$1 -1 Closed

SNTI Hedge Fund Activity: Q4 2025 in Review

15 of the 8,252 institutional investors tracked by Wall St. Rank reported a position in Senti Biosciences Holdings (SNTI) for Q4 2025, worth a combined $5.84M — down 29% from $8.27M a quarter earlier.

Sellers outnumbered buyers: 5 funds closed out of SNTI and 4 opened new positions — a net loss of 1 holder — while 2 trimmed existing stakes and 4 added.

The largest buyer was Virtu Financial, opening a new position worth an estimated $78.5K. The largest seller was 8VC GP I, exiting entirely with an estimated $358K sold.

  • 15 institutional investors held Senti Biosciences Holdings (SNTI) as of Q4 2025, down from 16 in Q3 2025.
  • Funds reported $5.84M of Senti Biosciences Holdings stock for Q4 2025, down 29% quarter-over-quarter.
  • 4 funds opened new Senti Biosciences Holdings positions in Q4 2025 and 5 closed out, a net change of -1 holder.
  • The largest Senti Biosciences Holdings buyer in Q4 2025 was Virtu Financial, an estimated $78.5K added.
  • The largest Senti Biosciences Holdings seller in Q4 2025 was 8VC GP I, an estimated $358K sold.

Based on aggregated 13F filings for Q4 2025.